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Your Environment. Your Health.

The Toxic Environment and the Epigenetics of Fetal Growth

Grant Number:
Principal Investigator:
Burris, Heather Herson
Institution:
Beth Israel Deaconess Medical Center
Most Recent Award Year:
2013
Lifestage of Participants:
Exposure: Prenatal; Adulthood (mother)
Assessment: Prenatal; Infant (0-1 year)
Exposures:
Metals: Arsenic
Health Outcomes:
Birth Outcomes: Birthweight
Biological Sample:
Umbilical cord blood leukocytes
Other Participant Data:
General diagnostics/Medical exam
Genes or Other DNA Products Studied:
Inflammatory cytokine genes; Glucocorticoid receptor gene
Epigenetic Mechanisms Studied:
DNA methylation
Abstract:

Related NIEHS-Funded Study Populations

Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT)

Principal Investigator:
Hu, Howard; Peterson, Karen; Hernandez-Avila, Mauricio; Tellez-Rojo, Martha Maria | Study Population Page Study Population c49
Institution:
University of Michigan
Location:
Mexico City, Mexico
Number of Participants::
1,653
Brief Description::
This is a group of three sequentially-enrolled, on-going, epidemiologic birth cohort studies in Mexico City with an original aim to investigate the impact of lead on child development. The research aims have since expanded to include a wide range health outcomes and environmental, nutritional, behavioral, genetic, and epigenetic risk factors. More than 1,600 mother-child pairs enrolled in the study beginning in 1994, some of whom have been followed for over two decades.
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