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Your Environment. Your Health.

Early Life Environmental Toxicant Exposure and Oral Health

Grant Number:
Principal Investigator:
Arora, Manish
Mount Sinai School of Medicine
Most Recent Award Year:
Lifestage of Participants:
Exposure: Prenatal; Infant (0-1 year); Youth (1-18 years); Adulthood (18+ years); Adulthood (mother)
Assessment: Youth (1-18 years); Adulthood (18+ years)
Metals: Arsenic; Cadmium; Lead; Manganese; Zinc
Health Outcomes:
Musculoskeletal Outcomes: Dental health
Biological Sample:
Blood; Shed deciduous teeth
Other Participant Data:
Dental caries and periodontal disease
Genes or Other DNA Products Studied:
Genes that regulate metal or calcium metabolism

Related NIEHS-Funded Study Populations

Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS)

Principal Investigator:
University of California, Berkeley
Salinas, California
Number of Participants::
~600 Mother-infant pairs
Brief Description::
This is a pregnancy study examining the effects, including the cumulative effects, of chemicals and other factors in the environment on children’s health among pregnant women and children living in the Salinas Valley, California. This study has enrolled approximately 600 participants since 1999.

Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT)

Principal Investigator:
Hu, Howard; Peterson, Karen; Hernandez-Avila, Mauricio; Tellez-Rojo, Martha Maria | Study Population Page Study Population c49
University of Michigan
Mexico City, Mexico
Number of Participants::
Brief Description::
This is a group of three sequentially-enrolled, on-going, epidemiologic birth cohort studies in Mexico City with an original aim to investigate the impact of lead on child development. The research aims have since expanded to include a wide range health outcomes and environmental, nutritional, behavioral, genetic, and epigenetic risk factors. More than 1,600 mother-child pairs enrolled in the study beginning in 1994, some of whom have been followed for over two decades.
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