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Molecular Mechanisms of Obesity in Children Exposed to Phthalates in Utero

Grant Number:
Principal Investigator:
Holland, Nina T
Institution:
University of California, Berkeley
Most Recent Award Year:
2013
Lifestage of Participants:
Exposure: Prenatal; Adulthood (mother)
Assessment: Prenatal; Youth (1-18 years, specifically 5-14 years of age)
Exposures:
Personal Care/Consumer Products: Phthalates
Health Outcomes:
Metabolic Outcomes: Metabolic syndrome; Obesity/body weight
Biological Sample:
Urine (mother)
Other Participant Data:
Waist circumference; BMI Z-score
Genes or Other DNA Products Studied:
Adiponectin; Leptin; Isoprostanes
Epigenetic Mechanisms Studied:
DNA methylation
Abstract:

Related NIEHS-Funded Study Populations

Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS)

Principal Investigator:
Institution:
University of California, Berkeley
Location:
Salinas, California
Number of Participants::
~600 Mother-infant pairs
Brief Description::
This is a pregnancy study examining the effects, including the cumulative effects, of chemicals and other factors in the environment on children’s health among pregnant women and children living in the Salinas Valley, California. This study has enrolled approximately 600 participants since 1999.
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