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Project 2: Metabolic Consequences of In Utero and Peripubertal Toxicant-Diet Exposures

Parent Title:
Lifecourse Exposures & Diet: Epigenetics, Maturation & Metabolic Syndrome
Grant Number:
Principal Investigator:
Peterson, Karen Eileen (Contact); Padmanabhan, Vasantha
Institution:
University of Michigan
Most Recent Award Year:
2013
Lifestage of Participants:
Exposure: Prenatal; Infant (0-1 year); Youth (1-18 years); Adulthood (mother)
Assessment: Infant (0-1 year); Youth (1-18 years)
Exposures:
Metals: Cadmium; Lead
Mixtures:
Nutrition/Diet/Supplements: Not specified
Personal Care/Consumer Products: Bisphenol A (BPA); Phthalates
Health Outcomes:
Metabolic Outcomes: Metabolic syndrome
Biological Sample:
Blood; Cord blood; Serum; Collected cells
Epigenetic Mechanisms Studied:
Epigenetic changes involved in altered metabolic function
Abstract:

Related NIEHS-Funded Study Populations

Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT)

Principal Investigator:
Hu, Howard; Peterson, Karen; Hernandez-Avila, Mauricio; Tellez-Rojo, Martha Maria | Study Population Page Study Population c49
Institution:
University of Michigan
Location:
Mexico City, Mexico
Number of Participants::
1,653
Brief Description::
This is a group of three sequentially-enrolled, on-going, epidemiologic birth cohort studies in Mexico City with an original aim to investigate the impact of lead on child development. The research aims have since expanded to include a wide range health outcomes and environmental, nutritional, behavioral, genetic, and epigenetic risk factors. More than 1,600 mother-child pairs enrolled in the study beginning in 1994, some of whom have been followed for over two decades.
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