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Your Environment. Your Health.

Children Exposure to SVOC Mixtures Indoors and Associations with Obesity

Grant Number:
Principal Investigator:
Stapleton, Heather M
Duke University
Most Recent Award Year:
Lifestage of Participants:
Exposure: Youth (1-18 years, specifically 1-4 years of age)
Assessment: Youth (1-18 years, specifically 1-4 years of age)
Air Pollutants: SVOCs
Health Outcomes:
Metabolic Outcomes: Obesity/body weight
Biological Sample:
Blood; Urine
Environmental Sample:
Home dust sample; Hand wipes from toddlers
Other Participant Data:
NEST follow-up questionnaire plus weight and height data
Genes or Other DNA Products Studied:
Peroxisome proliferator-activated nuclear receptors (PPARs)

Related NIEHS-Funded Study Populations

Newborn Epigenetics Study Cohort (NEST)

Principal Investigator:
Hoyo, Cathrine; Murphy, Susan | Study Population Page Study Population c178
Duke University
Durham, North Carolina
Number of Participants::
2,500 Mother-Infant Pairs
Brief Description::
This is a birth cohort study investigating how early life environmental exposures and nutrition affect DNA methylation profiles in newborns. Infants were followed throughout early childhood to determine if methylation profiles established in utero are associated with childhood obesity and neurobehavioral outcomes. Since 2004, NEST has enrolled more than 2,500 women in central North Carolina.
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