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Maternal and Paternal Flame Retardant Exposure, Impact on Fertility and Pregnancy

Grant Number:
Principal Investigator:
Hauser, Russ B (Contact); Meeker, John D
Harvard University
Most Recent Award Year:
Lifestage of Participants:
Exposure: Pre-conception; Prenatal; Adulthood (mother); Adulthood (father)
Assessment: Adulthood (mother); Adulthood (father)
Brominated Compounds: Polybrominated diphenyl ethers (PBDEs)
Organophosphate flame retardants :
Health Outcomes:
Birth Outcomes: Pregnancy outcomes
Reproductive Outcomes: Female fertility; Male fertility
Biological Sample:
Serum (mother, father); Urine (mother, father)
Other Participant Data:
Clinical measures of male fertility (semen quality and sperm damage); Fertilization rates; Spontaneous abortion; Implantation failure; Live birth rates

Related NIEHS-Funded Study Populations

Environment and Reproductive Health (EARTH) Study

Principal Investigator:
Harvard Chan School of Public Health
Number of Participants::
Brief Description::
This study is designed to determine the developmental and reproductive toxicity of mixtures of environmental chemicals, including phthalates and phenols in couples from a fertility clinic. Men and women were recruited at preconception and followed through treatment cycles for infertility and through pregnancy until delivery. Associations between environmental exposures and markers of male fertility and female fertility and pregnancy outcomes were investigated.
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