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PON Epigenetics and Neurodevelopment in Children

Grant Number:
Principal Investigator:
Holland, Nina T
University of California, Berkeley
Most Recent Award Year:
Lifestage of Participants:
Assessment: Infant (0-1 year); Adulthood (mother); Youth (1-18 years)
Health Outcomes:
Neurological/Cognitive Outcomes: Neurodevelopmental outcomes
Other Participant Data:
Cognition; Motor development; Attention
Genes or Other DNA Products Studied:
Paraoxonase 1 (PON1)
Epigenetic Mechanisms Studied:
DNA methylation; miRNA expression

Related NIEHS-Funded Study Populations

Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS)

Principal Investigator:
University of California, Berkeley
Salinas, California
Number of Participants::
~600 Mother-infant pairs
Brief Description::
This is a pregnancy study examining the effects, including the cumulative effects, of chemicals and other factors in the environment on children’s health among pregnant women and children living in the Salinas Valley, California. This study has enrolled approximately 600 participants since 1999.
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