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Methyl Mercury Effect on Adolescent Development Renewal

Grant Number:
Principal Investigator:
Davidson, Philip W
University of Rochester
Most Recent Award Year:
Lifestage of Participants:
Exposure: Prenatal; Infant (0-1 year); Youth (1-18 years); Adulthood (18+ years); Adulthood (mother)
Assessment: Adulthood (18+ years)
Metals: Mercury/methylmercury
Nutrition/Diet/Supplements: Polyunsaturated fatty acids (PUFAs)
Health Outcomes:
Cardiovascular Outcomes: Not specified
Neurological/Cognitive Outcomes: Neurobehavioral outcomes
Other Participant Data:
Neurocognitive function tests; Various heart function tests; Electrocardiogram; Arterial stiffness
Genes or Other DNA Products Studied:
C-reactive protein

Related NIEHS-Funded Study Populations

Seychelles Child Development and Nutrition Study (SCDNS)

Principal Investigator:
van Wijngaarden, Edwin; Davidson, Philip; Watson, Gene; Thurston, Sarah (Sally) W | Study Population Page Study Population c103
University of Rochester
The Seychelles
Number of Participants::
Brief Description::
This study, which began in the mid-1980s, includes several large cohorts of children whose mothers consumed fish frequently during their pregnancy. The study objective is to determine if prenatal methylmercury exposure from fish consumption has adverse effects on the children’s neurodevelopment as well as to document child development in the Seychelles. The Main cohort was recruited in 1989 and is comprised of 779 children. A subsequent Nutrition cohort (NC1) of 300 mothers was enrolled in 2001 during their first trimester of pregnancy. Most recently, a second Nutrition cohort (NC2) of 1,536 mother-child pairs was enrolled between 2008 and 2011.
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