Grant Number:
Principal Investigator:
Anderson, Kim A
Institution:
Oregon State University
Most Recent Award Year:
2015
Lifestage of Participants:
Exposure:
Prenatal; Adulthood (mother)
Assessment:
Adulthood (mother); Youth (1-18 years)
Exposures:
Air Pollutants:
Polycyclic aromatic hydrocarbons (PAHs)
Health Outcomes:
Respiratory Outcomes:
Asthma
Biological Sample:
Urine
Environmental Sample:
Air sample
Other Participant Data:
Questionnaire as one method of exposure assessment; Lung function (using spirometry)
Abstract:
Accurately assessing a person's exposures to putative environmental toxicants is central to the challenge of studying environmental health effects. The lack of low cost, easy-to-use personal sampling technology hinders epidemiological studies especially in disadvantaged populations. Our passive wristband sampler was developed to provide a relevant, quantifiable assessment. We propose to introduce an improved approach for measuring and characterizing polycyclic aromatic hydrocarbons (PAH) in disadvantaged communities. In phase 1 (R21), in an ongoing epidemiological cohort study of pregnant women in NYC, the performance of 4 exposure assessment methodologies will be evaluated with twenty-five pregnant volunteers recruited from a community health clinic located in northern Manhattan. In collaboration with a 501c3 environmental justice community organization, we have further advanced the passive wristband sampler to be an integrated mobile exposure device to capture uniquely-linked exposure and health information in their industrialized neighborhood in Eugene, Oregon. Upon completion of Phase 1 milestones, we will further assess the integration of personal exposure measurements with epidemiology studies of childhood respiratory symptoms in NYC and adult asthma exacerbation in Eugene to assess the relationships between air pollutants, location, and health outcomes in these disadvantaged communities. Through the R33 phase of this project, we will provide proof of principle demonstration that passive wristband samplers can be used for personalized exposure assessment and linkage to health outcomes. Data and results will be made available to our participants and their communities through novel and appropriate data visualization.
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Related NIEHS-Funded Study Populations
New York City Mothers and Newborns Study
Principal Investigator:
Perera, Frederica
| Study Population Page Study Population c25
Institution:
Columbia University
Location:
New York, New York
Number of Participants::
~725 Mother-infant pairs
Brief Description::
This is a birth cohort study of minority mothers and children in New York City that examines the effects of early life exposures to air pollutants, environmental tobacco smoke, pesticides, and endocrine disrupting chemicals on children's neurodevelopment, respiratory health, growth, and development. The study has recruited approximately 725 pregnant mothers since 1998.