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Human Exposure to Bisphenol A, Phthalates and Fertility, Pregnancy Outcomes

Grant Number:
Principal Investigator:
Hauser, Russ B
Institution:
Harvard University
Most Recent Award Year:
2009
Lifestage of Participants:
Exposure: Pre-conception; Prenatal; Adult (mother, specifically preconception, periconception, and throughout pregnancy)
Assessment: Adulthood (mother); Adulthood (father)
Exposures:
Personal Care/Consumer Products: Bisphenol A (BPA); Phthalates
Health Outcomes:
Birth Outcomes: Oocyte quality; Live birth rates; Pre-implantation embryo development
Reproductive Outcomes: Female fertility; Male fertility
Biological Sample:
Blood; Semen; Urine; Amniotic fluid; Ovarian follicular fluid
Abstract:

Related NIEHS-Funded Study Populations

Environment and Reproductive Health (EARTH) Study

Principal Investigator:
Institution:
Harvard Chan School of Public Health
Location:
Massachusetts
Number of Participants::
Recruiting
Brief Description::
This study is designed to determine the developmental and reproductive toxicity of mixtures of environmental chemicals, including phthalates and phenols in couples from a fertility clinic. Men and women were recruited at preconception and followed through treatment cycles for infertility and through pregnancy until delivery. Associations between environmental exposures and markers of male fertility and female fertility and pregnancy outcomes were investigated.
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