Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Your Environment. Your Health.

Collaborative Research and Action: Empowering an Exposed Community

Grant Number:
Principal Investigator:
Marcus, Michele
Institution:
Emory University
Most Recent Award Year:
2016
Lifestage of Participants:
Exposure: Prenatal; Infant (0-1 year); Youth (1-18 years); Adulthood (18+ years); Transgenerational
Assessment: Youth (1-18 years); Adulthood (18+ years)
Exposures:
Brominated Compounds: Polybrominated biphenyls (PBBs)
Nutrition/Diet/Supplements: Not specified
Health Outcomes:
Cancer Outcomes: Not specified
Immune Outcomes: Immune function
Liver/pancreatic problems:
Musculoskeletal Outcomes: Joint pain
Neurological/Cognitive Outcomes: Migraines; Neurodegenerative outcomes
Biological Sample:
Blood
Other Participant Data:
Health questionnaires
Epigenetic Mechanisms Studied:
DNA methylation within families to examine heritability of epigenetic marks associated with polybrominated biphenyl (PBB) exposure
Abstract:

Related NIEHS-Funded Study Populations

Michigan PBB Cohort

Principal Investigator:
Institution:
Emory University
Location:
Michigan
Number of Participants::
7,500
Brief Description::
This is a multi-generational cohort study to assess the effects of polybrominated biphenyl (PBB) exposure on a number of outcomes in men and women and their offspring after a widespread exposure incident in 1973. The Michigan PBB Registry was established in 1976 and enrolled approximately 4,000 farmers, chemical workers, and others with PBB exposure risk; children and grandchildren of original registrants have also been enrolled.
Back
to Top