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Neurobehavioral Effects of Insecticides Exposure in Pregnancy and Early Childhood

Grant Number:
Principal Investigator:
Yolton, Kimberly
Cincinnati Children's Hospital Medical Center
Most Recent Award Year:
Lifestage of Participants:
Exposure: Prenatal; Infant (0-1 year); Youth (1-18 years); Adulthood (mother)
Assessment: Infant (0-1 year); Youth (1-18 years)
Pesticides: Organophosphates; Pyrethroids
Health Outcomes:
Neurological/Cognitive Outcomes: Attention deficit hyperactivity disorder (ADHD); Neurobehavioral outcomes
Biological Sample:
Blood; Cord blood; Urine (mother, child)
Other Participant Data:
Behavioral/Cognitive tests; Questionnaire
Genes or Other DNA Products Studied:
Maternal and child DNA
Epigenetic Mechanisms Studied:
Impact of PON1 on associations between pesticide exposure and health and neurobehavioral outcomes

Related NIEHS-Funded Study Populations

Health Outcomes and Measures of the Environment (HOME) Study

Principal Investigator:
Lanphear, Bruce; Yolton, Kimberly; Cecil, Kim; Braun, Joseph; Chen, Aimin | Study Population Page Study Population c64
Cincinnati Children’s Hospital Medical Center
Cincinnati, Ohio
Number of Participants::
468 Mothers and 479 children
Brief Description::
This is a pregnancy and birth cohort study in Cincinnati to evaluate the impact of low-level fetal and childhood chemical exposures on health, developmental, and neurobehavioral outcomes. The study recruited over 400 pregnant women between 2003 to 2006. Offspring have been followed to age 12 years.
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