Parent Title:
Health Effects and Geochemistry of Arsenic
Grant Number:
Principal Investigator:
Van Geen, Alexander Frans
Institution:
Columbia University New York Morningside
Most Recent Award Year:
2017
Exposures:
Metals:
Arsenic
Health Outcomes:
Biological Sample:
Urine
Environmental Sample:
Drinking water sample
Other Participant Data:
Modeling the dynamics of urinary As in HEALS participants over time as a function of: their knowledge of the status with respect to As of their own and neighboring wells; geographic and social barriers to a low-As well; and awareness and education
Abstract:
Geoscience research conducted as part of this project focuses on the vulnerability of aquifers that are currently low in arsenic (As), but may become affected by human perturbations such as irrigation pumping and municipal pumping. These low-As aquifers are crucial for reducing As exposure for the Health of Effects of Arsenic Longitudinal Study (HEALS) cohort in Bangladesh, and throughout South and Southeast Asia. The approach builds on the premise that: a) iron oxide dissolution and precipitation control the partitioning of As between groundwater and aquifer sediments; and b) the supply of reactive organic carbon controls iron oxide dissolution and therefore the release of As to groundwater. The researchers are testing three hypotheses in collaboration with other projects and cores of the Columbia University Superfund Research Program Center:
• Whether irrigation pumping has redistributed As in shallow aquifers by enhanced lateral mixing
• Whether clay layers releasing organic carbon to deep, depressurized sandy aquifers pose a greater threat of As contamination than downward advection due to the lack of such clays
• Whether exposure to As can be predicted at the individual level from information available from the household including the status of its own and surrounding well(s), access to these wells, and awareness to the health risks of continued exposure.
ExpandCollapse Abstract
Related NIEHS-Funded Study Populations
Health Effects of Arsenic Longitudinal Study (HEALS)
Principal Investigator:
Ahsan, Habibul; Graziano, Joseph
| Study Population Page Study Population c63
Institution:
University of Chicago
Location:
Araihazar, Bangladesh
Number of Participants::
~35,000 recruited; Recruitment goal of 50,000
Brief Description::
This large prospective cohort study is based on individual-level data from a population exposed to a wide range of inorganic arsenic from drinking water in Araihazar, Bangladesh. Since 2000, the study has recruited more than 35,000 men and women with extensive questionnaire data, biological samples, drinking water samples, and diagnostic/clinical data.