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Your Environment. Your Health.

Follow-up and Maintenance of the Newborn Epigenetics STudy (NEST) Cohort

Grant Number:
Principal Investigator:
Hoyo, Cathrine
North Carolina State University
Most Recent Award Year:
Lifestage of Participants:
Exposure: Prenatal; Youth (1-18 years)
Assessment: Youth (1-18 years, specifically every 2 years until participants are 17 years of age)
Metals: Not specified
Other exposures including 23 inorganic, >70 organic compounds, and >100 nutrients:
Health Outcomes:
Cancer Outcomes: Obesity-related cancers
Cardiovascular Outcomes: Not specified
Metabolic Outcomes: Type 2 diabetes (T2D); Obesity/body weight
Other Participant Data:
Medical record data (weight, height, blood pressure, diagnoses and medications) abstracted every six months; Questionnare data

Related NIEHS-Funded Study Populations

Newborn Epigenetics Study Cohort (NEST)

Principal Investigator:
Hoyo, Cathrine; Murphy, Susan | Study Population Page Study Population c178
Duke University
Durham, North Carolina
Number of Participants::
2,500 Mother-Infant Pairs
Brief Description::
This is a birth cohort study investigating how early life environmental exposures and nutrition affect DNA methylation profiles in newborns. Infants were followed throughout early childhood to determine if methylation profiles established in utero are associated with childhood obesity and neurobehavioral outcomes. Since 2004, NEST has enrolled more than 2,500 women in central North Carolina.
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