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(http://www.niehs.nih.gov//portfolio/index.cfm?do=portfolio.grantdetail&&grant_number=K99ES035894&format=word)
| Principal Investigator: Alcala, Cecilia Sara | |
|---|---|
| Institute Receiving Award | Icahn School Of Medicine At Mount Sinai |
| Location | New York, NY |
| Grant Number | K99ES035894 |
| Funding Organization | National Institute of Environmental Health Sciences |
| Award Funding Period | 13 Mar 2024 to 28 Feb 2026 |
| DESCRIPTION (provided by applicant): | Summary I am an Environmental Health Scientist with training in environmental health literacy and global health and my primary research interests include investigating the role of environmental toxicant exposures, including mixtures, on child respiratory health and implementing effective strategies to increase environmental health literacy. The goal of this proposal is to enhance my knowledge and to obtain training in the skills needed to build my academic career by investigating prenatal pesticide exposure and child lung function and asthma outcomes, assessing environmental health literacy, and implementing effective dissemination strategies. Formal coursework and the expert mentorship of Drs. Kecia N. Carroll, Maria José Rosa, Maida Galvez, Robert O. Wright, Syam Andra, Shelley Liu, Elizabeth Roberts, and Hector Lamadrid-Figueroa will enable me to acquire the knowledge and skills necessary to become an independent transdisciplinary researcher. This training will allow me to achieve my short and long- term career goals: leading efforts to incorporate prenatal pesticide assessment and environmental health literacy into the ongoing Programming Research in Obesity, Growth, Environment, and Social Stressors (PROGRESS) cohort based in Mexico City in order to delineate prenatal pesticide effects on child lung function and asthma while engaging participants and the community to inform future interventions. I will train in 1) prenatal programming of child lung disease with Drs. Kecia N. Carroll and Maria José Rosa; 2) toxicology with Drs. Robert O. Wright and Syam Andra; 3) advanced statistical methods with Dr. Shelley Liu; 4) implementation science, translational research, and community outreach with Dr. Maida Galvez; 5) ethnographic and qualitative research approaches with Dr. Elizabeth Roberts; and 5) fieldwork management with Dr. Hector Lamadrid-Figueroa. I will integrate research on prenatal pesticides, lung function and asthma, and environmental health literacy through interactions with my mentorship team to become a transdisciplinary scientist. With their guidance, I will establish myself as an independent investigator with a tenure track faculty position and to position myself for a future R01. This proposal will address gaps regarding prenatal pesticide exposure in urban settings particularly in Latin America, associations with child adverse respiratory outcomes, and factors that may modify associations, as these are understudied research areas. The proposed research and training plan builds the foundation for an independent research career that aims to study prenatal environmental exposure effects on child respiratory health, environmental health literacy, and effective dissemination strategies. This study is also highly cost effective as we leverage the resources of the longitudinal PROGRESS study with existing biospecimens, lung function and other respiratory outcomes, and well-characterized covariate data. |
| Science Code(s)/Area of Science(s) |
Primary: 94 - Communication Research/Environmental Health Literacy Secondary: 03 - Carcinogenesis/Cell Transformation |
| Publications | No publications associated with this grant |
| Program Officer | Lindsey Martin |