| Project Title: | NEURONAL TARGETS AND MECHANISMS OF MANGANESE NEUROTOXICITY |
|---|---|
| PI: | Mukhopadhyay, Somshuvra |
| Institution: | University Of Texas At Austin |
| Grant Number: | R01ES024812 |
These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.
Viewing 19 publications
Export to Excel
(http://www.niehs.nih.gov//portfolio/index.cfm?do=portfolio.grantpubdetail&&grant_number=R01ES024812&format=excel)
| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Elevated thyroid manganese reduces thyroid iodine to induce hypothyroidism in mice, but not rats, la ... | Hutchens, Steven; Melkote, Ashvini; Jursa, Thomas; Shawlot, William; Trasande, Leonardo; Smith, ... | R01ES024812, R01ES031574 | Metallomics (2024 Jul 01) |
38866719
|
2024 |
| Loss of SLC30A10 manganese transporter alters expression of neurotransmission genes and activates hy ... | Warden, Anna; Mayfield, R Dayne; Gurol, Kerem C; Hutchens, Steven; Liu, Chunyi; Mukhopadhyay, ... | R01ES024812, R01ES031574 | Metallomics (2024 Feb 07) |
38285613
|
2024 |
| PHD2 enzyme is an intracellular manganese sensor that initiates the homeostatic response against ele ... | Gurol, Kerem C; Jursa, Thomas; Cho, Eun Jeong; Fast, Walter; Dalby, Kevin N; Smith, Donald R; ... | R01ES024812, R01ES031574 | Proc Natl Acad Sci U S A (2024 Jun 25) |
38905240
|
2024 |
| SLC30A10 manganese transporter in the brain protects against deficits in motor function and dopamine ... | Taylor, Cherish A; Grant, Stephanie M; Jursa, Thomas; Melkote, Ashvini; Fulthorpe, Rebecca; Asc ... | R01ES024812, R01ES031574 | Metallomics (2023 Apr 03) |
36990693
|
2023 |
| A genetically encoded fluorescent sensor for manganese(II), engineered from lanmodulin. | Park, Jennifer; Cleary, Michael B; Li, Danyang; Mattocks, Joseph A; Xu, Jiansong; Wang, Huan; ... | R01ES024812, R01ES031574 | Proc Natl Acad Sci U S A (2022 Dec 20) |
36508659
|
2022 |
| Role of excretion in manganese homeostasis and neurotoxicity: a historical perspective. | Gurol, Kerem C; Aschner, Michael; Smith, Donald R; Mukhopadhyay, Somshuvra | R01ES024812, R01ES031574 | Am J Physiol Gastrointest Liver Physiol (2022 Jan 01) |
34786983
|
2022 |
| Up-regulation of the manganese transporter SLC30A10 by hypoxia-inducible factors defines a homeostat ... | Liu, Chunyi; Jursa, Thomas; Aschner, Michael; Smith, Donald R; Mukhopadhyay, Somshuvra | R01ES024812, R01ES031574 | Proc Natl Acad Sci U S A (2021 08 31) |
34446561
|
2021 |
| Analysis of 1,25-Dihydroxyvitamin D3 Genomic Action Reveals Calcium-Regulating and Calcium-Independe ... | Li, Shanshan; De La Cruz, Jessica; Hutchens, Steven; Mukhopadhyay, Somshuvra; Criss, Zachary K; ... | R01ES024812 | Mol Cell Biol (2020 Dec 21) |
33139494
|
2020 |
| Brain manganese and the balance between essential roles and neurotoxicity. | Balachandran, Rekha C; Mukhopadhyay, Somshuvra; McBride, Danielle; Veevers, Jennifer; Harrison, ... | P30ES026529, R01ES010563, R01ES024812, R01ES031401 | J Biol Chem (2020 May 08) |
32188696
|
2020 |
| Maintaining Translational Relevance in Animal Models of Manganese Neurotoxicity. | Taylor, Cherish A; Tuschl, Karin; Nicolai, Merle M; Bornhorst, Julia; Gubert, Priscila; Varão, ... | R01ES007331, R01ES010563, R01ES024812 | J Nutr (2020 Jun 01) |
32211802
|
2020 |
| Generation and Validation of Tissue-Specific Knockout Strains for Toxicology Research. | Taylor, Cherish A; Shawlot, William; Ren, Jin Xiang; Mukhopadhyay, Somshuvra | R01ES024812 | Curr Protoc Toxicol (2019 09) |
31529798
|
2019 |
| SLC30A10 Mutation Involved in Parkinsonism Results in Manganese Accumulation within Nanovesicles of ... | Carmona, Asuncion; Zogzas, Charles E; Roudeau, Stéphane; Porcaro, Francesco; Garrevoet, Jan; Sp ... | R01ES024812 | ACS Chem Neurosci (2019 01 16) |
30272946
|
2019 |
| SLC30A10 transporter in the digestive system regulates brain manganese under basal conditions while ... | Taylor, Cherish A; Hutchens, Steven; Liu, Chunyi; Jursa, Thomas; Shawlot, William; Aschner, Mi ... | R01ES024812 | J Biol Chem (2019 02 08) |
30559290
|
2019 |
| Familial manganese-induced neurotoxicity due to mutations in SLC30A10 or SLC39A14. | Mukhopadhyay, Somshuvra | R01ES024812 | Neurotoxicology (2018 Jan) |
28789954
|
2018 |
| Putative metal binding site in the transmembrane domain of the manganese transporter SLC30A10 is dif ... | Zogzas, Charles E; Mukhopadhyay, Somshuvra | R01ES024812 | Metallomics (2018 Aug 15) |
29989630
|
2018 |
| Deficiency in the manganese efflux transporter SLC30A10 induces severe hypothyroidism in mice. | Hutchens, Steven; Liu, Chunyi; Jursa, Thomas; Shawlot, William; Chaffee, Beth K; Yin, Weiling; ... | R01ES024812 | J Biol Chem (2017 06 09) |
28461334
|
2017 |
| Hypothyroidism induced by loss of the manganese efflux transporter SLC30A10 may be explained by redu ... | Liu, Chunyi; Hutchens, Steven; Jursa, Thomas; Shawlot, William; Polishchuk, Elena V; Polishchuk ... | R01ES024812 | J Biol Chem (2017 10 06) |
28860195
|
2017 |
| Inherited Disorders of Manganese Metabolism. | Zogzas, Charles E; Mukhopadhyay, Somshuvra | R01ES024812 | Adv Neurobiol (2017) |
28889262
|
2017 |
| Structural Elements in the Transmembrane and Cytoplasmic Domains of the Metal Transporter SLC30A10 A ... | Zogzas, Charles E; Aschner, Michael; Mukhopadhyay, Somshuvra | R01ES024812 | J Biol Chem (2016 07 29) |
27307044
|
2016 |