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Who We Fund: Publication Detail

Project Title: INVESTIGATION OF HUMAN DNA POLYMERASE EPSILON VARIANTS
PI: Pursell, Zachary F
Institution: Tulane University Of Louisiana
Grant Number: R01ES028271

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Viewing 11 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Replication DNA polymerases, genome instability and cancer therapies.   Strauss, Juliet D; Pursell, Zachary F R01ES028271 NAR Cancer (2023 Sep) 37388540 Exiting the NIEHS site 2023 
Breast cancer cells survive chemotherapy by activating targetable immune-modulatory programs charact ...   Shahbandi, Ashkan; Chiu, Fang-Yen; Ungerleider, Nathan A; Kvadas, Raegan; Mheidly, Zeinab; Sun, ... R01ES028271, R01ES032036 Nat Cancer (2022 Dec) 36482233 Exiting the NIEHS site 2022 
Interlocking activities of DNA polymerase β in the base excision repair pathway.   Kumar, Adarsh; Reed, Andrew J; Zahurancik, Walter J; Daskalova, Sasha M; Hecht, Sidney M; Suo, ... R01ES028271 Proc Natl Acad Sci U S A (2022 Mar 08) 35238634 Exiting the NIEHS site 2022 
DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal an ...   Chung, Jiil; Maruvka, Yosef E; Sudhaman, Sumedha; Kelly, Jacalyn; Haradhvala, Nicholas J; Bianc ... R01ES028271 Cancer Discov (2021 05) 33355208 Exiting the NIEHS site 2021 
Dynamic Processing of a Common Oxidative DNA Lesion by the First Two Enzymes of the Base Excision Re ...   Raper, Austin T; Maxwell, Brian A; Suo, Zucai R01ES028271 J Mol Biol (2021 03 05) 33450252 Exiting the NIEHS site 2021 
Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenes ...   Galati, Melissa A; Hodel, Karl P; Gams, Miki S; Sudhaman, Sumedha; Bridge, Taylor; Zahurancik, ... R01ES028271 Cancer Res (2020 Dec 15) 32938641 Exiting the NIEHS site 2020 
Kinetic investigation of the polymerase and exonuclease activities of human DNA polymerase ε holoenz ...   Zahurancik, Walter J; Suo, Zucai R01ES028271 J Biol Chem (2020 Dec 11) 33051204 Exiting the NIEHS site 2020 
POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair S ...   Hodel, Karl P; Sun, Meijuan J S; Ungerleider, Nathan; Park, Vivian S; Williams, Leonard G; Baue ... R01ES028271 Mol Cell (2020 Jun 18) 32497495 Exiting the NIEHS site 2020 
POLE proofreading defects: Contributions to mutagenesis and cancer.   Park, Vivian S; Pursell, Zachary F R01ES028271 DNA Repair (Amst) (2019 Apr) 30818169 Exiting the NIEHS site 2019 
Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is dri ...   Hodel, Karl P; de Borja, Richard; Henninger, Erin E; Campbell, Brittany B; Ungerleider, Nathan; ... R01ES028271 Elife (2018 02 28) 29488881 Exiting the NIEHS site 2018 
Comprehensive Analysis of Hypermutation in Human Cancer.   Campbell, Brittany B; Light, Nicholas; Fabrizio, David; Zatzman, Matthew; Fuligni, Fabio; de Bo ... R01ES028271 Cell (2017 Nov 16) 29056344 Exiting the NIEHS site 2017 
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