| Project Title: | INVESTIGATION OF HUMAN DNA POLYMERASE EPSILON VARIANTS |
|---|---|
| PI: | Pursell, Zachary F |
| Institution: | Tulane University Of Louisiana |
| Grant Number: | R01ES028271 |
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Replication DNA polymerases, genome instability and cancer therapies. | Strauss, Juliet D; Pursell, Zachary F | R01ES028271 | NAR Cancer (2023 Sep) |
37388540
|
2023 |
| Breast cancer cells survive chemotherapy by activating targetable immune-modulatory programs charact ... | Shahbandi, Ashkan; Chiu, Fang-Yen; Ungerleider, Nathan A; Kvadas, Raegan; Mheidly, Zeinab; Sun, ... | R01ES028271, R01ES032036 | Nat Cancer (2022 Dec) |
36482233
|
2022 |
| Interlocking activities of DNA polymerase β in the base excision repair pathway. | Kumar, Adarsh; Reed, Andrew J; Zahurancik, Walter J; Daskalova, Sasha M; Hecht, Sidney M; Suo, ... | R01ES028271 | Proc Natl Acad Sci U S A (2022 Mar 08) |
35238634
|
2022 |
| DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal an ... | Chung, Jiil; Maruvka, Yosef E; Sudhaman, Sumedha; Kelly, Jacalyn; Haradhvala, Nicholas J; Bianc ... | R01ES028271 | Cancer Discov (2021 05) |
33355208
|
2021 |
| Dynamic Processing of a Common Oxidative DNA Lesion by the First Two Enzymes of the Base Excision Re ... | Raper, Austin T; Maxwell, Brian A; Suo, Zucai | R01ES028271 | J Mol Biol (2021 03 05) |
33450252
|
2021 |
| Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenes ... | Galati, Melissa A; Hodel, Karl P; Gams, Miki S; Sudhaman, Sumedha; Bridge, Taylor; Zahurancik, ... | R01ES028271 | Cancer Res (2020 Dec 15) |
32938641
|
2020 |
| Kinetic investigation of the polymerase and exonuclease activities of human DNA polymerase ε holoenz ... | Zahurancik, Walter J; Suo, Zucai | R01ES028271 | J Biol Chem (2020 Dec 11) |
33051204
|
2020 |
| POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair S ... | Hodel, Karl P; Sun, Meijuan J S; Ungerleider, Nathan; Park, Vivian S; Williams, Leonard G; Baue ... | R01ES028271 | Mol Cell (2020 Jun 18) |
32497495
|
2020 |
| POLE proofreading defects: Contributions to mutagenesis and cancer. | Park, Vivian S; Pursell, Zachary F | R01ES028271 | DNA Repair (Amst) (2019 Apr) |
30818169
|
2019 |
| Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is dri ... | Hodel, Karl P; de Borja, Richard; Henninger, Erin E; Campbell, Brittany B; Ungerleider, Nathan; ... | R01ES028271 | Elife (2018 02 28) |
29488881
|
2018 |
| Comprehensive Analysis of Hypermutation in Human Cancer. | Campbell, Brittany B; Light, Nicholas; Fabrizio, David; Zatzman, Matthew; Fuligni, Fabio; de Bo ... | R01ES028271 | Cell (2017 Nov 16) |
29056344
|
2017 |