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Who We Fund: Publication Detail

Project Title: APE1 CLEAVAGE MECHANISMS DURING DNA REPAIR
PI: Freudenthal, Bret D
Institution: University Of Kansas Medical Center
Grant Number: R01ES029203

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Viewing 13 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Oxidative DNA damage on the VEGF G-quadruplex forming promoter is repaired via long-patch BER.   Hussen, Adil S; Kravitz, Haley L; Freudenthal, Bret D; Whitaker, Amy M R00ES031148, R01ES029203 Environ Mol Mutagen (2024 Apr) 37606505 Exiting the NIEHS site 2024 
Generation of Recombinant Nucleosomes Containing Site-Specific DNA Damage.   Ryan, Benjamin J; Weaver, Tyler M; Spencer, Jonah J; Freudenthal, Bret D R01ES029203 Methods Mol Biol (2023) 37574475 Exiting the NIEHS site 2023 
Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimi ...   Hoitsma, Nicole M; Norris, Jessica; Khoang, Thu H; Kaushik, Vikas; Chadda, Rahul; Antony, Edwi ... R01ES029203 Nucleic Acids Res (2023 Jul 21) 37264933 Exiting the NIEHS site 2023 
Visualizing the coordination of apurinic/apyrimidinic endonuclease (APE1) and DNA polymerase β durin ...   Fairlamb, Max S; Spies, Maria; Washington, M Todd; Freudenthal, Bret D R01ES029203 J Biol Chem (2023 May) 36963489 Exiting the NIEHS site 2023 
Processing oxidatively damaged bases at DNA strand breaks by APE1.   Whitaker, Amy M; Stark, Wesley J; Freudenthal, Bret D R00ES031148, R01ES029203 Nucleic Acids Res (2022 Sep 09) 36018803 Exiting the NIEHS site 2022 
Structural basis for APE1 processing DNA damage in the nucleosome.   Weaver, Tyler M; Hoitsma, Nicole M; Spencer, Jonah J; Gakhar, Lokesh; Schnicker, Nicholas J; Fr ... R01ES029203 Nat Commun (2022 Sep 14) 36104361 Exiting the NIEHS site 2022 
Transcriptional regulation via strand displacement DNA repair in G-quadruplexes.   Whitaker, Amy; Freudenthal, Bret R01ES029203 FASEB J (2022 May) 35556471 Exiting the NIEHS site 2022 
Altered APE1 activity on abasic ribonucleotides is mediated by changes in the nucleoside sugar pucke ...   Hoitsma, Nicole M; Click, Timothy H; Agarwal, Pratul K; Freudenthal, Bret D R01ES029203 Comput Struct Biotechnol J (2021) 34188778 Exiting the NIEHS site 2021 
Construction of a Three-Color Prism-Based TIRF Microscope to Study the Interactions and Dynamics of ...   Fairlamb, Max S; Whitaker, Amy M; Bain, Fletcher E; Spies, Maria; Freudenthal, Bret D R01ES029203 Biology (Basel) (2021 Jun 23) 34201434 Exiting the NIEHS site 2021 
AP-endonuclease 1 sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop.   Hoitsma, Nicole M; Whitaker, Amy M; Beckwitt, Emily C; Jang, Sunbok; Agarwal, Pratul K; Van Hou ... R01ES029203 Nucleic Acids Res (2020 07 27) 32542366 Exiting the NIEHS site 2020 
Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance.   McNeill, Daniel R; Whitaker, Amy M; Stark, Wesley J; Illuzzi, Jennifer L; McKinnon, Peter J; Fr ... R01ES029203 Mutagenesis (2020 02 13) 31816044 Exiting the NIEHS site 2020 
History of DNA polymerase β X-ray crystallography.   Whitaker, Amy M; Freudenthal, Bret D R01ES029203 DNA Repair (Amst) (2020 09) 33087265 Exiting the NIEHS site 2020 
Molecular and structural characterization of disease-associated APE1 polymorphisms.   Whitaker, Amy M; Stark, Wesley J; Flynn, Tony S; Freudenthal, Bret D R01ES029203 DNA Repair (Amst) (2020 Jul - Aug) 32454397 Exiting the NIEHS site 2020 
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