Project Title: | DNA ADDUCT-INDUCED MUTAGENESIS |
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PI: | Stone, Michael P |
Institution: | Vanderbilt University |
Grant Number: | R01ES029357 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Replication Bypass of the N-(2-Deoxy-d-erythro-pentofuranosyl)-urea DNA Lesion by Human DNA Polymera ... | Tomar, Rachana; Li, Songlin; Egli, Martin; Stone, Michael P | R01ES029357 | Biochemistry (2024 Mar 19) | 38413007 | 2024 |
The aflatoxin B1-induced imidazole ring-opened guanine adduct: High mutagenic potential that is mini ... | Minko, Irina G; Kellum Jr, Andrew H; Stone, Michael P; Lloyd, R Stephen | R01ES029357, R01ES031086 | Environ Mol Mutagen (2024 Apr) | 37303259 | 2024 |
Base-Displaced Intercalated Structure of the 3-(2-Deoxy-β-D-erythropentofuranosyl)-pyrimido[1,2-f]pu ... | Fu, Yizhi; Christov, Plamen P; Kingsley, Philip J; Richie-Jannetta, Robyn M; Marnett, Lawrence ... | R01ES029357 | Chem Res Toxicol (2023 Dec 18) | 37989274 | 2023 |
Endogenous Metabolites and Genome Instability in Aging and Disease. | Tomar, Rachana; Erber, Luke | R01ES029357, R13ES035636 | Chem Res Toxicol (2023 Dec 18) | 37947799 | 2023 |
Functional analyses of single nucleotide polymorphic variants of the DNA glycosylase NEIL1 in sub-Sa ... | Zuckerman, Jamie T; Minko, Irina G; Kant, Melis; Jaruga, Pawel; Stone, Michael P; Dizdaroglu, ... | R01ES029357, R01ES031086 | DNA Repair (Amst) (2023 Sep) | 37517321 | 2023 |
Conformation and Pairing Properties of an O6-Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleos ... | Kellum Jr, Andrew H; Pallan, Pradeep S; Nilforoushan, Arman; Sturla, Shana J; Stone, Michael P; ... | R01ES029357, T32ES018827 | Chem Res Toxicol (2022 Oct 17) | 35973057 | 2022 |
Polymorphic variant Asp239Tyr of human DNA glycosylase NTHL1 is inactive for removal of a variety of ... | Kant, Melis; Quintana, Victoria; Coskun, Erdem; Jaruga, Pawel; Lloyd, R Stephen; Sweasy, Joann ... | R01ES029357, R01ES031086 | DNA Repair (Amst) (2022 Sep) | 35870279 | 2022 |
Beyond ribose and phosphate: Selected nucleic acid modifications for structure-function investigatio ... | Liczner, Christopher; Duke, Kieran; Juneau, Gabrielle; Egli, Martin; Wilds, Christopher J | R01ES029357 | Beilstein J Org Chem (2021) | 33981365 | 2021 |
DNA Sequence Modulates the Efficiency of NEIL1-Catalyzed Excision of the Aflatoxin B1-Induced Formam ... | Tomar, Rachana; Minko, Irina G; Kellum Jr, Andrew H; Voehler, Markus W; Stone, Michael P; McCul ... | R01ES029357, R01ES031086 | Chem Res Toxicol (2021 03 15) | 33595290 | 2021 |
Structure of a Stable Interstrand DNA Cross-Link Involving a β-N-Glycosyl Linkage Between an N6-dA A ... | Kellum Jr, Andrew H; Qiu, David Y; Voehler, Markus W; Martin, William; Gates, Kent S; Stone, M ... | R01ES029357 | Biochemistry (2021 01 12) | 33382597 | 2021 |
Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1. | Minko, Irina G; Vartanian, Vladimir L; Tozaki, Naoto N; Coskun, Erdem; Coskun, Sanem Hosbas; Ja ... | R01ES029357, R01ES031086 | DNA Repair (Amst) (2020 01) | 31733589 | 2020 |
Aflatoxin-Guanine DNA Adducts and Oxidatively Induced DNA Damage in Aflatoxin-Treated Mice in Vivo a ... | Coskun, Erdem; Jaruga, Pawel; Vartanian, Vladimir; Erdem, Onur; Egner, Patricia A; Groopman, J ... | R01ES029357, R01ES031086 | Chem Res Toxicol (2019 01 22) | 30525498 | 2019 |
Characterization of rare NEIL1 variants found in East Asian populations. | Minko, Irina G; Vartanian, Vladimir L; Tozaki, Naoto N; Linde, Oskar K; Jaruga, Pawel; Coskun, ... | R01ES029357 | DNA Repair (Amst) (2019 07) | 31100703 | 2019 |
Human DNA polymerase η has reverse transcriptase activity in cellular environments. | Su, Yan; Ghodke, Pratibha P; Egli, Martin; Li, Lin; Wang, Yinsheng; Guengerich, F Peter | R01ES029357 | J Biol Chem (2019 04 12) | 30842261 | 2019 |
Mechanisms underlying aflatoxin-associated mutagenesis - Implications in carcinogenesis. | McCullough, Amanda K; Lloyd, R Stephen | R01ES029357 | DNA Repair (Amst) (2019 05) | 30897375 | 2019 |
Processing of N5-substituted formamidopyrimidine DNA adducts by DNA glycosylases NEIL1 and NEIL3. | Minko, Irina G; Christov, Plamen P; Li, Liang; Stone, Michael P; McCullough, Amanda K; Lloyd, ... | R01ES029357 | DNA Repair (Amst) (2019 01) | 30448017 | 2019 |
Configurational and Conformational Equilibria of N6-(2-Deoxy-d-erythro-pentofuranosyl)-2,6-diamino-3 ... | Bamberger, Stephanie N; Malik, Chanchal K; Voehler, Markus W; Brown, Summer K; Pan, Hope; Johns ... | R01ES029357, T32ES007028 | Chem Res Toxicol (2018 09 17) | 30169026 | 2018 |
Patterns of growth and tract formation during the early development of secondary lineages in the Dro ... | Lovick, Jennifer K; Kong, Angel; Omoto, Jaison J; Ngo, Kathy T; Younossi-Hartenstein, Amelia; H ... | R01ES029357 | Dev Neurobiol (2016 Apr) | 26178322 | 2016 |
Origin and development of neuropil glia of the Drosophila larval and adult brain: Two distinct glial ... | Omoto, Jaison Jiro; Yogi, Puja; Hartenstein, Volker | R01ES029357 | Dev Biol (2015 Aug 15) | 25779704 | 2015 |
Postembryonic lineages of the Drosophila brain: I. Development of the lineage-associated fiber tract ... | Lovick, Jennifer K; Ngo, Kathy T; Omoto, Jaison J; Wong, Darren C; Nguyen, Joseph D; Hartenstei ... | R01ES029357 | Dev Biol (2013 Dec 15) | 23880429 | 2013 |