Project Title: | AHR-DEPENDENT PKM2 REGULATION IN NAFLD PROGRESSION |
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PI: | Zacharewski, Timothy R. |
Institution: | Michigan State University |
Grant Number: | R01ES029541 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Inhibition of the urea cycle by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin in ... | Cholico, Giovan N; Fling, Russell R; Sink, Warren J; Nault, Rance; Zacharewski, Tim | P42ES004911, R01ES029541, T32ES007255 | J Biol Chem (2024 Jan) | 38013089 | 2024 |
Consequences of reprogramming acetyl-CoA metabolism by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mo ... | Cholico, Giovan N; Orlowska, Karina; Fling, Russell R; Sink, Warren J; Zacharewski, Nicholas A; ... | P42ES004911, R01ES029541, T32ES007255 | Sci Rep (2023 Mar 13) | 36914879 | 2023 |
Cystine/Glutamate Xc- Antiporter Induction Compensates for Transsulfuration Pathway Repression by 2, ... | Orlowska, Karina; Fling, Russ R; Nault, Rance; Schilmiller, Anthony L; Zacharewski, Timothy R | P42ES004911, R01ES029541, T32ES007255 | Chem Res Toxicol (2023 Jun 19) | 37184393 | 2023 |
Benchmarking of a Bayesian single cell RNAseq differential gene expression test for dose-response st ... | Nault, Rance; Saha, Satabdi; Bhattacharya, Sudin; Dodson, Jack; Sinha, Samiran; Maiti, Tapabra ... | P42ES004911, R01ES029541 | Nucleic Acids Res (2022 May 06) | 35061903 | 2022 |
Dioxin-elicited decrease in cobalamin redirects propionyl-CoA metabolism to the β-oxidation-like pat ... | Orlowska, Karina; Fling, Russ R; Nault, Rance; Sink, Warren J; Schilmiller, Anthony L; Zacharew ... | P42ES004911, R01ES029541, R01ES033898, T32ES007255 | J Biol Chem (2022 Sep) | 35931118 | 2022 |
Genome-Wide ChIPseq Analysis of AhR, COUP-TF, and HNF4 Enrichment in TCDD-Treated Mouse Liver. | Cholico, Giovan N; Nault, Rance; Zacharewski, Tim R | P42ES004911, R01ES029541, T32ES007255 | Int J Mol Sci (2022 Jan 29) | 35163483 | 2022 |
Aryl Hydrocarbon Receptor (AhR) Activation by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Dose-Depend ... | Fling, Russell R; Zacharewski, Timothy R | P42ES004911, R01ES029541, T32ES007255 | Int J Mol Sci (2021 Nov 18) | 34830313 | 2021 |
Genetics-Based Approach to Identify Novel Genes Regulated by the Aryl Hydrocarbon Receptor in Mouse ... | Jurgelewicz, Amanda; Dornbos, Peter; Warren, Melanie; Nault, Rance; Arkatkar, Anooj; Lin, Hui; ... | P42ES004911, R01ES029541, T32ES007255 | Toxicol Sci (2021 May 27) | 33720361 | 2021 |
Single-Nuclei RNA Sequencing Assessment of the Hepatic Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxi ... | Nault, Rance; Fader, Kelly A; Bhattacharya, Sudin; Zacharewski, Tim R | P42ES004911, R01ES029541 | Cell Mol Gastroenterol Hepatol (2021) | 32791302 | 2021 |
Thioesterase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin results in a futile cycle that inhibit ... | Cholico, Giovan N; Fling, Russell R; Zacharewski, Nicholas A; Fader, Kelly A; Nault, Rance; Zac ... | P42ES004911, R01ES029541, T32ES007255 | Sci Rep (2021 08 03) | 34344994 | 2021 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the pro ... | Fling, Russell R; Doskey, Claire M; Fader, Kelly A; Nault, Rance; Zacharewski, Tim R | P42ES004911, R01ES029541, T32ES007255 | Sci Rep (2020 09 09) | 32908189 | 2020 |