| Project Title: | CHROMATIN REGIONS, GENES AND PATHWAYS THAT CONFER SUSCEPTIBILITY TO CHEMICAL-INDUCED DNA DAMAGE |
|---|---|
| PI: | Rusyn, Ivan |
| Institution: | Texas A&M Agrilife Research |
| Grant Number: | R01ES029911 |
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Viewing 21 publications
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Incorporating new approach methods (NAMs) data in dose-response assessments: The future is now! | Lu, En-Hsuan; Rusyn, Ivan; Chiu, Weihsueh A | P30ES029067, P42ES027704, R01ES029911 | J Toxicol Environ Health B Crit Rev (2025 Jan 02) |
39390665
|
2025 |
| A preclinical model of severe NASH-like liver injury by chronic administration of a high-fat and hig ... | Willett, Rose A; Tryndyak, Volodymyr P; Hughes Hanks, Jennifer M; Elkins, Lana; Nagumalli, Sure ... | R01ES029911 | Toxicol Appl Pharmacol (2024 Oct) |
39084266
|
2024 |
| Refining risk estimates for lead in drinking water based on the impact of genetics and diet on blood ... | Cuomo, Danila; Nitcher, Megan; Barba, Estefania; Feinberg, Andrew P; Rusyn, Ivan; Chiu, Weihsu ... | P30ES029067, P42ES027704, R01ES029911 | Toxicol Sci (2023 Jul 28) |
37243727
|
2023 |
| Simultaneous modeling of multivariate heterogeneous responses and heteroskedasticity via a two-stage ... | Ting, Bryan W; Wright, Fred A; Zhou, Yi-Hui | R01ES029911, R01ES033243, T32ES007329 | Biom J (2023 Aug) |
37212427
|
2023 |
| A Population-Based Human In Vitro Approach to Quantify Inter-Individual Variability in Responses to ... | Ford, Lucie C; Jang, Suji; Chen, Zunwei; Zhou, Yi-Hui; Gallins, Paul J; Wright, Fred A; Chiu, ... | P30ES029067, P42ES027704, R01ES029911, T32ES026568 | Toxics (2022 Aug 01) |
36006120
|
2022 |
| A resource for integrated genomic analysis of the human liver. | Zhou, Yi-Hui; Gallins, Paul J; Etheridge, Amy S; Jima, Dereje; Scholl, Elizabeth; Wright, Fred ... | P30ES010126, P42ES027704, R01ES029911 | Sci Rep (2022 Sep 07) |
36071064
|
2022 |
| Characterization of population variability of 1,3-butadiene derived protein adducts in humans and mi ... | Boysen, Gunnar; Rusyn, Ivan; Chiu, Weihsueh A; Wright, Fred A | P30ES029067, P42ES027704, R01ES029911 | Regul Toxicol Pharmacol (2022 Jul) |
35469930
|
2022 |
| Cumulative Risk Meets Inter-Individual Variability: Probabilistic Concentration Addition of Complex ... | Jang, Suji; Ford, Lucie C; Rusyn, Ivan; Chiu, Weihsueh A | P30ES029067, P42ES027704, R01ES029911, T32ES026568 | Toxics (2022 Sep 20) |
36287830
|
2022 |
| Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogen ... | Goodman, Samantha; Chappell, Grace; Guyton, Kathryn Z; Pogribny, Igor P; Rusyn, Ivan | R01ES029911, T32ES026568 | Mutat Res Rev Mutat Res (2022) |
35690411
|
2022 |
| Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fa ... | Nagumalli, Suresh K; Willett, Rose A; de Conti, Aline; Tryndyak, Volodymyr P; Avigan, Mark I; d ... | R01ES029911 | J Nutr Biochem (2022 Nov) |
35858665
|
2022 |
| Model systems and organisms for addressing inter- and intra-species variability in risk assessment. | Rusyn, Ivan; Chiu, Weihsueh A; Wright, Fred A | P30ES029067, P42ES027704, R01ES029911 | Regul Toxicol Pharmacol (2022 Jul) |
35636685
|
2022 |
| Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the ... | Tryndyak, Volodymyr P; Willett, Rose A; Avigan, Mark I; Sanyal, Arun J; Beland, Frederick A; Ru ... | R01ES029911 | Epigenetics (2022 Nov) |
35324388
|
2022 |
| Effects of GSTT1 Genotype on the Detoxification of 1,3-Butadiene Derived Diepoxide and Formation of ... | Boysen, Gunnar; Arora, Rashi; Degner, Amanda; Vevang, Karin R; Chao, Christopher; Rodriguez, F ... | R01ES029911 | Chem Res Toxicol (2021 01 18) |
33381973
|
2021 |
| Intra- and Inter-Species Variability in Urinary N7-(1-Hydroxy-3-buten-2-yl)guanine Adducts Following ... | Erber, Luke; Goodman, Samantha; Wright, Fred A; Chiu, Weihsueh A; Tretyakova, Natalia Y; Rusyn, ... | R01ES029911, T32ES026568 | Chem Res Toxicol (2021 Nov 15) |
34726909
|
2021 |
| Proteome-Wide Profiling of Cellular Targets Modified by Dopamine Metabolites Using a Bio-Orthogonall ... | Hurben, Alexander K; Erber, Luke N; Tretyakova, Natalia Y; Doran, Todd M | R01ES023350, R01ES029911 | ACS Chem Biol (2021 Nov 19) |
34726906
|
2021 |
| Quantitative NanoLC/NSI+-HRMS Method for 1,3-Butadiene Induced bis-N7-guanine DNA-DNA Cross-Links in ... | Erber, Luke; Goodman, Samantha; Jokipii Krueger, Caitlin C; Rusyn, Ivan; Tretyakova, Natalia | R01ES029911, T32ES026568 | Toxics (2021 Oct 02) |
34678943
|
2021 |
| Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patt ... | Keele, Gregory R; Quach, Bryan C; Israel, Jennifer W; Chappell, Grace A; Lewis, Lauren; Safi, ... | P30ES010126, P30ES025128, R01ES029911 | PLoS Genet (2020 Jan) |
31961859
|
2020 |
| Interindividual Differences in DNA Adduct Formation and Detoxification of 1,3-Butadiene-Derived Epox ... | Degner, Amanda; Arora, Rashi; Erber, Luke; Chao, Christopher; Peterson, Lisa A; Tretyakova, Na ... | R01ES029911 | Chem Res Toxicol (2020 07 20) |
32237725
|
2020 |
| Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse. | Lewis, Lauren; Borowa-Mazgaj, Barbara; de Conti, Aline; Chappell, Grace A; Luo, Yu-Syuan; Bodna ... | R01ES029911 | Chem Res Toxicol (2019 05 20) |
30990016
|
2019 |
| Sex-specific differences in genotoxic and epigenetic effects of 1,3-butadiene among mouse tissues. | Lewis, Lauren; Chappell, Grace A; Kobets, Tetyana; O'Brian, Bridget E; Sangaraju, Dewakar; Kosy ... | P30ES025128, P30ES029067, R01ES029911 | Arch Toxicol (2019 Mar) |
30552462
|
2019 |
| Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Pop ... | Luo, Yu-Syuan; Cichocki, Joseph A; Hsieh, Nan-Hung; Lewis, Lauren; Wright, Fred A; Threadgill, ... | P30ES029067, P42ES027704, R01ES029911 | Environ Health Perspect (2019 06) |
31246107
|
2019 |