| Project Title: | IMPROVED METHODS FOR INFERENCE OF GENOTYPE-SPECIFIC RESPONSE TO ENVIRONMENTAL TOXINS |
|---|---|
| PI: | Ayroles, Julien |
| Institution: | Princeton University |
| Grant Number: | R01ES029929 |
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Viewing 28 publications
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Reassessing the modularity of gene co-expression networks using the Stochastic Block Model. | Melo, Diogo; Pallares, Luisa F; Ayroles, Julien F | R01ES029929 | bioRxiv (2024 Apr 10) |
37398186
|
2024 |
| Applying an evolutionary mismatch framework to understand disease susceptibility. | Lea, Amanda J; Clark, Andrew G; Dahl, Andrew W; Devinsky, Orrin; Garcia, Angela R; Golden, Chr ... | R01ES029929 | PLoS Biol (2023 Sep) |
37695771
|
2023 |
| Capturing continuous, long timescale behavioral changes in Drosophila melanogaster postural data. | McKenzie-Smith, Grace C; Wolf, Scott W; Ayroles, Julien F; Shaevitz, Joshua W | R01ES029929 | ArXiv (2023 Sep 07) |
37731659
|
2023 |
| Characterizing the landscape of gene expression variance in humans. | Wolf, Scott; Melo, Diogo; Garske, Kristina M; Pallares, Luisa F; Lea, Amanda J; Ayroles, Julie ... | F32ES034668, R01ES029929 | PLoS Genet (2023 Jul) |
37410774
|
2023 |
| Dietary stress remodels the genetic architecture of lifespan variation in outbred Drosophila. | Pallares, Luisa F; Lea, Amanda J; Han, Clair; Filippova, Elena V; Andolfatto, Peter; Ayroles, ... | R01ES029929 | Nat Genet (2023 Jan) |
36550361
|
2023 |
| Disease risk and healthcare utilization among ancestrally diverse groups in the Los Angeles region. | Caggiano, Christa; Boudaie, Arya; Shemirani, Ruhollah; Mefford, Joel; Petter, Ella; Chiu, Alec ... | R01ES029929 | Nat Med (2023 Jul) |
37464048
|
2023 |
| Cross-trait assortative mating is widespread and inflates genetic correlation estimates. | Border, Richard; Athanasiadis, Georgios; Buil, Alfonso; Schork, Andrew J; Cai, Na; Young, Alex ... | R01ES029929 | Science (2022 Nov 18) |
36395242
|
2022 |
| Diverse environmental perturbations reveal the evolution and context-dependency of genetic effects o ... | Lea, Amanda J; Peng, Julie; Ayroles, Julien F | R01ES029929 | Genome Res (2022 Oct) |
36229124
|
2022 |
| Massively parallel analysis of human 3' UTRs reveals that AU-rich element length and registration pr ... | Siegel, David A; Le Tonqueze, Olivier; Biton, Anne; Zaitlen, Noah; Erle, David J | R01ES029929 | G3 (Bethesda) (2022 Jan 04) |
34849835
|
2022 |
| Methylation risk scores are associated with a collection of phenotypes within electronic health reco ... | Thompson, Mike; Hill, Brian L; Rakocz, Nadav; Chiang, Jeffrey N; Geschwind, Daniel; Sankararama ... | R01ES029929 | NPJ Genom Med (2022 Aug 25) |
36008412
|
2022 |
| Multi-context genetic modeling of transcriptional regulation resolves novel disease loci. | Thompson, Mike; Gordon, Mary Grace; Lu, Andrew; Tandon, Anchit; Halperin, Eran; Gusev, Alexand ... | R01ES029929 | Nat Commun (2022 Sep 28) |
36171194
|
2022 |
| Study Protocol: Interactive Dynamics of Coral Reef Fisheries and the Nutrition Transition in Kiribat ... | Golden, Christopher D; Ayroles, Julien; Eurich, Jacob G; Gephart, Jessica A; Seto, Katherine L; ... | R01ES029929 | Front Public Health (2022) |
35719655
|
2022 |
| A model and test for coordinated polygenic epistasis in complex traits. | Sheppard, Brooke; Rappoport, Nadav; Loh, Po-Ru; Sanders, Stephan J; Zaitlen, Noah; Dahl, Andy | R01ES029929 | Proc Natl Acad Sci U S A (2021 Apr 13) |
33833052
|
2021 |
| A polygenic-score-based approach for identification of gene-drug interactions stratifying breast can ... | Marderstein, Andrew R; Kulm, Scott; Peng, Cheng; Tamimi, Rulla; Clark, Andrew G; Elemento, Oli ... | R01ES029929 | Am J Hum Genet (2021 Sep 02) |
34363748
|
2021 |
| Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE. | Caggiano, Christa; Celona, Barbara; Garton, Fleur; Mefford, Joel; Black, Brian L; Henderson, R ... | R01ES029929 | Nat Commun (2021 05 11) |
33976150
|
2021 |
| Constructing germline research cohorts from the discarded reads of clinical tumor sequences. | Gusev, Alexander; Groha, Stefan; Taraszka, Kodi; Semenov, Yevgeniy R; Zaitlen, Noah | R01ES029929 | Genome Med (2021 11 08) |
34749793
|
2021 |
| Design and analysis of CRISPR-based underdominance toxin-antidote gene drives. | Champer, Jackson; Champer, Samuel E; Kim, Isabel K; Clark, Andrew G; Messer, Philipp W | R01ES029929 | Evol Appl (2021 Apr) |
33897820
|
2021 |
| Disentangling selection on genetically correlated polygenic traits via whole-genome genealogies. | Stern, Aaron J; Speidel, Leo; Zaitlen, Noah A; Nielsen, Rasmus | R01ES029929 | Am J Hum Genet (2021 Feb 04) |
33440170
|
2021 |
| Meta-analysis suggests the microbiome responds to Evolve and Resequence experiments in Drosophila me ... | Henry, Lucas P; Ayroles, Julien F | R01ES029929 | BMC Microbiol (2021 Apr 09) |
33836662
|
2021 |
| Suppression gene drive in continuous space can result in unstable persistence of both drive and wild ... | Champer, Jackson; Kim, Isabel K; Champer, Samuel E; Clark, Andrew G; Messer, Philipp W | R01ES029929 | Mol Ecol (2021 02) |
33404162
|
2021 |
| A CRISPR homing gene drive targeting a haplolethal gene removes resistance alleles and successfully ... | Champer, Jackson; Yang, Emily; Lee, Esther; Liu, Jingxian; Clark, Andrew G; Messer, Philipp W | R01ES029929 | Proc Natl Acad Sci U S A (2020 Sep 29) |
32929034
|
2020 |
| A Robust Method Uncovers Significant Context-Specific Heritability in Diverse Complex Traits. | Dahl, Andy; Nguyen, Khiem; Cai, Na; Gandal, Michael J; Flint, Jonathan; Zaitlen, Noah | R01ES029929 | Am J Hum Genet (2020 Jan 02) |
31901249
|
2020 |
| Computational and experimental performance of CRISPR homing gene drive strategies with multiplexed g ... | Champer, Samuel E; Oh, Suh Yeon; Liu, Chen; Wen, Zhaoxin; Clark, Andrew G; Messer, Philipp W; ... | R01ES029929 | Sci Adv (2020 Mar) |
32181354
|
2020 |
| Efficient Estimation and Applications of Cross-Validated Genetic Predictions to Polygenic Risk Score ... | Mefford, Joel; Park, Danny; Zheng, Zhili; Ko, Arthur; Ala-Korpela, Mika; Laakso, Markku; Pajuk ... | R01ES029929 | J Comput Biol (2020 04) |
32077750
|
2020 |
| Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic background ... | Rau, Christoph D; Gonzales, Natalia M; Bloom, Joshua S; Park, Danny; Ayroles, Julien; Palmer, ... | R01ES029929 | PLoS Genet (2020 10) |
33104702
|
2020 |
| The Evolution of Variance Control. | Bruijning, Marjolein; Metcalf, C Jessica E; Jongejans, Eelke; Ayroles, Julien F | R01ES029929 | Trends Ecol Evol (2020 Jan) |
31519463
|
2020 |
| TM3'seq: A Tagmentation-Mediated 3' Sequencing Approach for Improving Scalability of RNAseq Experime ... | Pallares, Luisa F; Picard, Serge; Ayroles, Julien F | R01ES029929 | G3 (Bethesda) (2020 01 07) |
31676507
|
2020 |
| Genetic and environmental perturbations lead to regulatory decoherence. | Lea, Amanda; Subramaniam, Meena; Ko, Arthur; Lehtimäki, Terho; Raitoharju, Emma; Kähönen, Mika ... | R01ES029929 | Elife (2019 Mar 05) |
30834892
|
2019 |