| Project Title: | ROLE AND MECHANISMS OF EXCRETION IN MANGANESE NEUROTOXICITY |
|---|---|
| PI: | Mukhopadhyay, Somshuvra |
| Institution: | University Of Texas At Austin |
| Grant Number: | R01ES031574 |
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Elevated thyroid manganese reduces thyroid iodine to induce hypothyroidism in mice, but not rats, la ... | Hutchens, Steven; Melkote, Ashvini; Jursa, Thomas; Shawlot, William; Trasande, Leonardo; Smith, ... | R01ES024812, R01ES031574 | Metallomics (2024 Jul 01) |
38866719
|
2024 |
| Loss of SLC30A10 manganese transporter alters expression of neurotransmission genes and activates hy ... | Warden, Anna; Mayfield, R Dayne; Gurol, Kerem C; Hutchens, Steven; Liu, Chunyi; Mukhopadhyay, ... | R01ES024812, R01ES031574 | Metallomics (2024 Feb 07) |
38285613
|
2024 |
| PHD2 enzyme is an intracellular manganese sensor that initiates the homeostatic response against ele ... | Gurol, Kerem C; Jursa, Thomas; Cho, Eun Jeong; Fast, Walter; Dalby, Kevin N; Smith, Donald R; ... | R01ES024812, R01ES031574 | Proc Natl Acad Sci U S A (2024 Jun 25) |
38905240
|
2024 |
| Hepatic and intestinal manganese excretion are both required to regulate brain manganese during elev ... | Hutchens, Steven; Jursa, Thomas P; Melkote, Ashvini; Grant, Stephanie M; Smith, Donald R; Mukho ... | R01ES031574 | Am J Physiol Gastrointest Liver Physiol (2023 Sep 01) |
37461848
|
2023 |
| Manganese efflux transporter SLC30A10 missense polymorphism T95I associated with liver injury retain ... | Gurol, Kerem C; Li, Danyang; Broberg, Karin; Mukhopadhyay, Somshuvra | R01ES031574 | Am J Physiol Gastrointest Liver Physiol (2023 Jan 01) |
36414535
|
2023 |
| SLC30A10 manganese transporter in the brain protects against deficits in motor function and dopamine ... | Taylor, Cherish A; Grant, Stephanie M; Jursa, Thomas; Melkote, Ashvini; Fulthorpe, Rebecca; Asc ... | R01ES024812, R01ES031574 | Metallomics (2023 Apr 03) |
36990693
|
2023 |
| A genetically encoded fluorescent sensor for manganese(II), engineered from lanmodulin. | Park, Jennifer; Cleary, Michael B; Li, Danyang; Mattocks, Joseph A; Xu, Jiansong; Wang, Huan; ... | R01ES024812, R01ES031574 | Proc Natl Acad Sci U S A (2022 Dec 20) |
36508659
|
2022 |
| Role of excretion in manganese homeostasis and neurotoxicity: a historical perspective. | Gurol, Kerem C; Aschner, Michael; Smith, Donald R; Mukhopadhyay, Somshuvra | R01ES024812, R01ES031574 | Am J Physiol Gastrointest Liver Physiol (2022 Jan 01) |
34786983
|
2022 |
| Up-regulation of the manganese transporter SLC30A10 by hypoxia-inducible factors defines a homeostat ... | Liu, Chunyi; Jursa, Thomas; Aschner, Michael; Smith, Donald R; Mukhopadhyay, Somshuvra | R01ES024812, R01ES031574 | Proc Natl Acad Sci U S A (2021 08 31) |
34446561
|
2021 |