Project Title: | R-LOOPS AT THE TELOMERE AS A TOXIC SOURCE OF GENOMIC INSTABILITY |
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PI: | Griffith, Jack D |
Institution: | Univ Of North Carolina Chapel Hill |
Grant Number: | R01ES031635 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Binding of microRNA-122 to the hepatitis C virus 5' untranslated region modifies interactions with p ... | Scott, Seth; Li, You; Bermek, Oya; Griffith, Jack D; Lemon, Stanley M; Choi, Kyung H | R01ES031635 | Nucleic Acids Res (2023 Dec 11) | 37941151 | 2023 |
Electron microscopy mapping of the DNA-binding sites of monomeric, dimeric, and multimeric KSHV RTA ... | Calhoun, Jayla C; Damania, Blossom; Griffith, Jack D; Costantini, Lindsey M | R01ES031635 | J Virol (2023 Oct 31) | 37750723 | 2023 |
Large-scale heparin-based bind-and-elute chromatography identifies two biologically distinct populat ... | Zhou, Yijun; Yuan, Runjie; Cone, Allaura S; Shifflett, Kyle W; Arias, Gabriel F; Peng, Alice; ... | R01ES031635 | J Extracell Vesicles (2023 Jun) | 37272197 | 2023 |
Mammalian telomeric RNA (TERRA) can be translated to produce valine-arginine and glycine-leucine dip ... | Al-Turki, Taghreed M; Griffith, Jack D | R01ES031635 | Proc Natl Acad Sci U S A (2023 Feb 28) | 36812212 | 2023 |
Exosome-Encased Nucleic Acid Scaffold Chemotherapeutic Agents for Superior Anti-Tumor and Anti-Angio ... | McNamara, Ryan P; Eason, Anthony B; Zhou, Yijun; Bigi, Rachele; Griffith, Jack D; Costantini, ... | R01ES031635 | ACS Bio Med Chem Au (2022 Apr 20) | 35480227 | 2022 |
Imaging of surface microdomains on individual extracellular vesicles in 3-D. | McNamara, Ryan P; Zhou, Yijun; Eason, Anthony B; Landis, Justin T; Chambers, Meredith G; Willco ... | R01ES031635 | J Extracell Vesicles (2022 Mar) | 35234354 | 2022 |
Peptide Amphiphile Supramolecular Nanofibers Designed to Target Abdominal Aortic Aneurysms. | Ledford, Benjamin T; Akerman, Adam W; Sun, Kui; Gillis, David C; Weiss, Jenna M; Vang, Johnny; ... | R01ES031635 | ACS Nano (2022 May 24) | 35504018 | 2022 |
Residues located in the primase domain of the bacteriophage T7 primase-helicase are essential for lo ... | Hernandez, Alfredo J; Lee, Seung-Joo; Thompson, Noah J; Griffith, Jack D; Richardson, Charles C | R01ES031635 | J Biol Chem (2022 Jun) | 35500649 | 2022 |
The interplay of RNA:DNA hybrid structure and G-quadruplexes determines the outcome of R-loop-replis ... | Kumar, Charanya; Batra, Sahil; Griffith, Jack D; Remus, Dirk | R01ES031635 | Elife (2021 09 08) | 34494544 | 2021 |
The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replicati ... | Jiang, Min; Xie, Xie; Zhu, Xuefeng; Jiang, Shan; Milenkovic, Dusanka; Misic, Jelena; Shi, Yon ... | R01ES031635 | Sci Adv (2021 07) | 34215584 | 2021 |
Electron microscopic characterization of exhaust particles containing lead dibromide beads expelled ... | Griffith, Jack D | R01ES031635 | Atmos Pollut Res (2020 Sep) | 33100835 | 2020 |
Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cance ... | Tsutakawa, Susan E; Sarker, Altaf H; Ng, Clifford; Arvai, Andrew S; Shin, David S; Shih, Brian ... | R01ES031635 | Proc Natl Acad Sci U S A (2020 06 23) | 32522879 | 2020 |
Mitochondrial dysfunction and DNA damage accompany enhanced levels of formaldehyde in cultured prima ... | Nadalutti, Cristina A; Stefanick, Donna F; Zhao, Ming-Lang; Horton, Julie K; Prasad, Rajendra; ... | R01ES031635 | Sci Rep (2020 03 27) | 32221313 | 2020 |
Twenty years of t-loops: A case study for the importance of collaboration in molecular biology. | Tomáška, Ľubomír; Cesare, Anthony J; AlTurki, Taghreed M; Griffith, Jack D | R01ES031635 | DNA Repair (Amst) (2020 10) | 32620538 | 2020 |