| Project Title: | DETECTING MUTATIONAL SIGNATURES OF ENVIRONMENTAL MUTAGENS IN HEATHY INDIVIDUALS FOR PERSONALIZED CANCER PREVENTION |
|---|---|
| PI: | Alexandrov, Ludmil B |
| Institution: | University Of California, San Diego |
| Grant Number: | R01ES032547 |
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes ac ... | Thatikonda, Venu; Islam, S M Ashiqul; Autry, Robert J; Jones, Barbara C; Gröbner, Susanne N; Wa ... | R01ES032547 | Nat Cancer (2023 Feb) |
36702933
|
2023 |
| DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer. | Zhivagui, Maria; Hoda, Areebah; Valenzuela, Noelia; Yeh, Yi-Yu; Dai, Jason; He, Yudou; Nandi, ... | R01ES032547, R35ES031638 | Nat Commun (2023 Jan 17) |
36650165
|
2023 |
| Unraveling the impact of a germline heterozygous POLD1 frameshift variant in serrated polyposis synd ... | Bonjoch, Laia; Soares de Lima, Yasmin; Díaz-Gay, Marcos; Dotti, Isabella; Muñoz, Jenifer; Morei ... | R01ES032547 | Front Mol Biosci (2023) |
36756361
|
2023 |
| An overview of mutational and copy number signatures in human cancer. | Steele, Christopher D; Pillay, Nischalan; Alexandrov, Ludmil B | R01ES032547 | J Pathol (2022 Jul) |
35420163
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2022 |
| Examining clustered somatic mutations with SigProfilerClusters. | Bergstrom, Erik N; Kundu, Mousumy; Tbeileh, Noura; Alexandrov, Ludmil B | R01ES032547 | Bioinformatics (2022 Jun 27) |
35595234
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2022 |
| Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA. | Bergstrom, Erik N; Luebeck, Jens; Petljak, Mia; Khandekar, Azhar; Barnes, Mark; Zhang, Tongwu; ... | R01ES032547 | Nature (2022 Feb) |
35140399
|
2022 |
| Mechanisms of APOBEC3 mutagenesis in human cancer cells. | Petljak, Mia; Dananberg, Alexandra; Chu, Kevan; Bergstrom, Erik N; Striepen, Josefine; von Morg ... | R01ES032547 | Nature (2022 Jul) |
35859169
|
2022 |
| Signatures of copy number alterations in human cancer. | Steele, Christopher D; Abbasi, Ammal; Islam, S M Ashiqul; Bowes, Amy L; Khandekar, Azhar; Haase ... | R01ES032547 | Nature (2022 Jun) |
35705804
|
2022 |
| Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor. | Islam, S M Ashiqul; Díaz-Gay, Marcos; Wu, Yang; Barnes, Mark; Vangara, Raviteja; Bergstrom, Er ... | R01ES032547 | Cell Genom (2022 Nov 09) |
36388765
|
2022 |
| Genomic and evolutionary classification of lung cancer in never smokers. | Zhang, Tongwu; Joubert, Philippe; Ansari-Pour, Naser; Zhao, Wei; Hoang, Phuc H; Lokanga, Rache ... | R01ES032547 | Nat Genet (2021 09) |
34493867
|
2021 |
| Significance and limitations of the use of next-generation sequencing technologies for detecting mut ... | Abbasi, Ammal; Alexandrov, Ludmil B | R01ES032547 | DNA Repair (Amst) (2021 11) |
34411908
|
2021 |