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Your Environment. Your Health.

Who We Fund: Publication Detail

Project Title: DETECTING MUTATIONAL SIGNATURES OF ENVIRONMENTAL MUTAGENS IN HEATHY INDIVIDUALS FOR PERSONALIZED CANCER PREVENTION
PI: Alexandrov, Ludmil B
Institution: University Of California, San Diego
Grant Number: R01ES032547

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 11 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm?do=portfolio.grantpubdetail&&grant_number=R01ES032547&format=excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes ac ...   Thatikonda, Venu; Islam, S M Ashiqul; Autry, Robert J; Jones, Barbara C; Gröbner, Susanne N; Wa ... R01ES032547 Nat Cancer (2023 Feb) 36702933 Exiting the NIEHS site 2023 
DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer.   Zhivagui, Maria; Hoda, Areebah; Valenzuela, Noelia; Yeh, Yi-Yu; Dai, Jason; He, Yudou; Nandi, ... R01ES032547, R35ES031638 Nat Commun (2023 Jan 17) 36650165 Exiting the NIEHS site 2023 
Unraveling the impact of a germline heterozygous POLD1 frameshift variant in serrated polyposis synd ...   Bonjoch, Laia; Soares de Lima, Yasmin; Díaz-Gay, Marcos; Dotti, Isabella; Muñoz, Jenifer; Morei ... R01ES032547 Front Mol Biosci (2023) 36756361 Exiting the NIEHS site 2023 
An overview of mutational and copy number signatures in human cancer.   Steele, Christopher D; Pillay, Nischalan; Alexandrov, Ludmil B R01ES032547 J Pathol (2022 Jul) 35420163 Exiting the NIEHS site 2022 
Examining clustered somatic mutations with SigProfilerClusters.   Bergstrom, Erik N; Kundu, Mousumy; Tbeileh, Noura; Alexandrov, Ludmil B R01ES032547 Bioinformatics (2022 Jun 27) 35595234 Exiting the NIEHS site 2022 
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA.   Bergstrom, Erik N; Luebeck, Jens; Petljak, Mia; Khandekar, Azhar; Barnes, Mark; Zhang, Tongwu; ... R01ES032547 Nature (2022 Feb) 35140399 Exiting the NIEHS site 2022 
Mechanisms of APOBEC3 mutagenesis in human cancer cells.   Petljak, Mia; Dananberg, Alexandra; Chu, Kevan; Bergstrom, Erik N; Striepen, Josefine; von Morg ... R01ES032547 Nature (2022 Jul) 35859169 Exiting the NIEHS site 2022 
Signatures of copy number alterations in human cancer.   Steele, Christopher D; Abbasi, Ammal; Islam, S M Ashiqul; Bowes, Amy L; Khandekar, Azhar; Haase ... R01ES032547 Nature (2022 Jun) 35705804 Exiting the NIEHS site 2022 
Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor.   Islam, S M Ashiqul; Díaz-Gay, Marcos; Wu, Yang; Barnes, Mark; Vangara, Raviteja; Bergstrom, Er ... R01ES032547 Cell Genom (2022 Nov 09) 36388765 Exiting the NIEHS site 2022 
Genomic and evolutionary classification of lung cancer in never smokers.   Zhang, Tongwu; Joubert, Philippe; Ansari-Pour, Naser; Zhao, Wei; Hoang, Phuc H; Lokanga, Rache ... R01ES032547 Nat Genet (2021 09) 34493867 Exiting the NIEHS site 2021 
Significance and limitations of the use of next-generation sequencing technologies for detecting mut ...   Abbasi, Ammal; Alexandrov, Ludmil B R01ES032547 DNA Repair (Amst) (2021 11) 34411908 Exiting the NIEHS site 2021 
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