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Who We Fund: Publication Detail

Project Title: BARCODED HUMAN CELLS ENGINEERED WITH HETEROZYGOUS GENETIC DIVERSITY TO UNCOVER TOXICODYNAMIC VARIABILITY
PI: George, Jay
Institution: Amelia Technologies, Llc
Grant Number: R44ES032522

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Viewing 14 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
CHK1 inhibitor induced PARylation by targeting PARG causes excessive replication and metabolic stres ...   Acharya, Ganesh; Mani, Chinnadurai; Sah, Naresh; Saamarthy, Karunakar; Young, Robert; Reedy, M ... P01ES028949, R44ES032522, U01ES029518, U01ES029518 Cell Death Discov (2024 Jun 11) 38862485 Exiting the NIEHS site 2024 
Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in th ...   Almohdar, Danah; Gulkis, Mitchell; Ortiz, Abigail; Tang, Qun; Sobol, Robert W; Çağlayan, Melik ... P01ES028949, R44ES032522, U01ES029518, U01ES029518 J Mol Biol (2024 Feb 15) 38135179 Exiting the NIEHS site 2024 
Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson.   Yan, Shan; Gaddameedhi, Shobhan; Sobol, Robert W P01ES028949, P30ES025128, R01ES030113, R21ES032966, R44ES032522, U01ES029518, U01ES029518 Environ Mol Mutagen (2024 Apr) 38619433 Exiting the NIEHS site 2024 
Mouse models to explore the biological and organismic role of DNA polymerase beta.   Sobol, Robert W P01ES028949, R44ES032522, U01ES029518, U01ES029518 Environ Mol Mutagen (2024 Apr) 38619421 Exiting the NIEHS site 2024 
A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonucle ...   Das, Debanu; Duncton, Matthew A J; Georgiadis, Taxiarchis M; Pellicena, Patricia; Clark, Jennif ... P01ES028949, R44ES032522, U01ES029518, U01ES029518 Int J Mol Sci (2023 Nov 23) 38068959 Exiting the NIEHS site 2023 
Editorial: DNA repair and nucleic acid therapeutics in cancer.   Sobol, Robert W P01ES028949, R44ES032522, U01ES029518, U01ES029518 NAR Cancer (2023 Sep) 37645072 Exiting the NIEHS site 2023 
Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA dama ...   Al-Rahahleh, Rasha Q; Saville, Kate M; Andrews, Joel F; Wu, Zhijin; Koczor, Christopher A; Sobo ... P01ES028949, R44ES032522, U01ES029518, U01ES029518 bioRxiv (2023 Dec 29) 38234836 Exiting the NIEHS site 2023 
Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without ...   Koczor, Christopher A; Thompson, Marlo K; Sharma, Nidhi; Prakash, Aishwarya; Sobol, Robert W P01ES028949, R01ES030084, R44ES032522, U01ES029518, U01ES029518 DNA Repair (Amst) (2023 Mar) 36702010 Exiting the NIEHS site 2023 
Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage.   Koczor, Christopher A; Saville, Kate M; Al-Rahahleh, Rasha Q; Andrews, Joel F; Li, Jianfeng; So ... P01ES028949, R44ES032522, U01ES029518, U01ES029518 Methods Mol Biol (2023) 36515828 Exiting the NIEHS site 2023 
WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/misma ...   Sobol, Robert W P01ES028949, R44ES032522, U01ES029518, U01ES029518 Proc Natl Acad Sci U S A (2023 Jan 10) 36598947 Exiting the NIEHS site 2023 
A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular res ...   Li, Jianfeng; Beiser, Alison; Dey, Nupur B; Takeda, Shunichi; Saha, Liton Kumar; Hirota, Kouji ... R44ES032522, U01ES029518, U01ES029518 NAR Genom Bioinform (2022 Sep) 36110898 Exiting the NIEHS site 2022 
Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens.   Koczor, Christopher A; Haider, Aaron J; Saville, Kate M; Li, Jianfeng; Andrews, Joel F; Beiser, ... P01ES028949, R44ES032522, U01ES029518, U01ES029518 Cancers (Basel) (2022 Jul 28) 35954352 Exiting the NIEHS site 2022 
Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair.   Thompson, Marlo K; Sobol, Robert W; Prakash, Aishwarya P01ES028949, R01ES030084, R35ES031708, R44ES032522, U01ES029518, U01ES029518 Biology (Basel) (2021 Jun 14) 34198612 Exiting the NIEHS site 2021 
Primary saturation of α, β-unsaturated carbonyl containing fatty acids does not abolish electrophili ...   Snyder, Nathaniel W; O'Brien, James; Singh, Bhupinder; Buchan, Gregory; Arroyo, Alejandro D; Li ... P01ES028949, P30ES013508, R44ES032522, U01ES029518, U01ES029518 Chem Biol Interact (2021 Dec 01) 34634267 Exiting the NIEHS site 2021 
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