| Project Title: | BARCODED HUMAN CELLS ENGINEERED WITH HETEROZYGOUS GENETIC DIVERSITY TO UNCOVER TOXICODYNAMIC VARIABILITY |
|---|---|
| PI: | George, Jay |
| Institution: | Amelia Technologies, Llc |
| Grant Number: | R44ES032522 |
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Viewing 15 publications
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| CHK1 inhibitor induced PARylation by targeting PARG causes excessive replication and metabolic stres ... | Acharya, Ganesh; Mani, Chinnadurai; Sah, Naresh; Saamarthy, Karunakar; Young, Robert; Reedy, M ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Cell Death Discov (2024 Jun 11) |
38862485
|
2024 |
| Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in th ... | Almohdar, Danah; Gulkis, Mitchell; Ortiz, Abigail; Tang, Qun; Sobol, Robert W; Çağlayan, Melik ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | J Mol Biol (2024 Feb 15) |
38135179
|
2024 |
| Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson. | Yan, Shan; Gaddameedhi, Shobhan; Sobol, Robert W | P01ES028949, P30ES025128, R01ES030113, R21ES032966, R44ES032522, U01ES029518, U01ES029518 | Environ Mol Mutagen (2024 Apr) |
38619433
|
2024 |
| Mouse models to explore the biological and organismic role of DNA polymerase beta. | Sobol, Robert W | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Environ Mol Mutagen (2024 Apr) |
38619421
|
2024 |
| Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhanc ... | Saville, Kate M; Al-Rahahleh, Rasha Q; Siddiqui, Aisha H; Andrews, Morgan E; Roos, Wynand P; Ko ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | DNA Repair (Amst) (2024 Aug) |
38897003
|
2024 |
| A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonucle ... | Das, Debanu; Duncton, Matthew A J; Georgiadis, Taxiarchis M; Pellicena, Patricia; Clark, Jennif ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Int J Mol Sci (2023 Nov 23) |
38068959
|
2023 |
| Editorial: DNA repair and nucleic acid therapeutics in cancer. | Sobol, Robert W | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | NAR Cancer (2023 Sep) |
37645072
|
2023 |
| Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA dama ... | Al-Rahahleh, Rasha Q; Saville, Kate M; Andrews, Joel F; Wu, Zhijin; Koczor, Christopher A; Sobo ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | bioRxiv (2023 Dec 29) |
38234836
|
2023 |
| Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without ... | Koczor, Christopher A; Thompson, Marlo K; Sharma, Nidhi; Prakash, Aishwarya; Sobol, Robert W | P01ES028949, R01ES030084, R44ES032522, U01ES029518, U01ES029518 | DNA Repair (Amst) (2023 Mar) |
36702010
|
2023 |
| Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage. | Koczor, Christopher A; Saville, Kate M; Al-Rahahleh, Rasha Q; Andrews, Joel F; Li, Jianfeng; So ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Methods Mol Biol (2023) |
36515828
|
2023 |
| WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/misma ... | Sobol, Robert W | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Proc Natl Acad Sci U S A (2023 Jan 10) |
36598947
|
2023 |
| A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular res ... | Li, Jianfeng; Beiser, Alison; Dey, Nupur B; Takeda, Shunichi; Saha, Liton Kumar; Hirota, Kouji ... | R44ES032522, U01ES029518, U01ES029518 | NAR Genom Bioinform (2022 Sep) |
36110898
|
2022 |
| Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens. | Koczor, Christopher A; Haider, Aaron J; Saville, Kate M; Li, Jianfeng; Andrews, Joel F; Beiser, ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Cancers (Basel) (2022 Jul 28) |
35954352
|
2022 |
| Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair. | Thompson, Marlo K; Sobol, Robert W; Prakash, Aishwarya | P01ES028949, R01ES030084, R35ES031708, R44ES032522, U01ES029518, U01ES029518 | Biology (Basel) (2021 Jun 14) |
34198612
|
2021 |
| Primary saturation of α, β-unsaturated carbonyl containing fatty acids does not abolish electrophili ... | Snyder, Nathaniel W; O'Brien, James; Singh, Bhupinder; Buchan, Gregory; Arroyo, Alejandro D; Li ... | P01ES028949, P30ES013508, R44ES032522, U01ES029518, U01ES029518 | Chem Biol Interact (2021 Dec 01) |
34634267
|
2021 |