Project Title: | THE WASHU TARGET ENVIRONMENTAL EPIGENOMICS DATA COORDINATION CENTER |
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PI: | Wang, Ting |
Institution: | Washington University |
Grant Number: | U24ES026699 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Capture Methylation-Sensitive Restriction Enzyme Sequencing (Capture MRE-Seq) for Methylation Analys ... | Xing, Xiaoyun; Karlow, Jennifer A; Li, Daofeng; Jang, Hyo Sik; Lee, Hyung Joo; Wang, Ting | U24ES026699 | Methods Mol Biol (2023) |
37041441
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2023 |
Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements. | Shah, Nakul M; Jang, H Josh; Liang, Yonghao; Maeng, Ju Heon; Tzeng, Shin-Cheng; Wu, Angela; Ba ... | U24ES026699 | Nat Genet (2023 Apr) |
36973455
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2023 |
Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes. | Choudhary, Mayank N K; Quaid, Kara; Xing, Xiaoyun; Schmidt, Heather; Wang, Ting | U24ES026699 | Nat Commun (2023 Feb 06) |
36746940
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2023 |
Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis. | Karlow, Jennifer A; Devarakonda, Siddhartha; Xing, Xiaoyun; Jang, Hyo Sik; Govindan, Ramaswamy; ... | U24ES026699 | Cancer Res (2022 Aug 03) |
35706127
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2022 |
Epigenomic analysis reveals prevalent contribution of transposable elements to cis-regulatory elemen ... | Lee, Hyung Joo; Hou, Yiran; Maeng, Ju Heon; Shah, Nakul M; Chen, Yujie; Lawson, Heather A; Yan ... | U24ES026699 | Genome Res (2022 Jul) |
35649578
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2022 |
Exploring genomic data coupled with 3D chromatin structures using the WashU Epigenome Browser. | Li, Daofeng; Harrison, Jessica K; Purushotham, Deepak; Wang, Ting | U24ES026699 | Nat Methods (2022 Aug) |
35864166
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2022 |
Genetic, epigenetic, and environmental mechanisms govern allele-specific gene expression. | St Pierre, Celine L; Macias-Velasco, Juan F; Wayhart, Jessica P; Yin, Li; Semenkovich, Clay F; ... | U24ES026699 | Genome Res (2022 Jun) |
35501130
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2022 |
Mammalian genome innovation through transposon domestication. | Modzelewski, Andrew J; Gan Chong, Johnny; Wang, Ting; He, Lin | U24ES026699 | Nat Cell Biol (2022 Sep) |
36008480
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2022 |
WashU Epigenome Browser update 2022. | Li, Daofeng; Purushotham, Deepak; Harrison, Jessica K; Hsu, Silas; Zhuo, Xiaoyu; Fan, Changxu; ... | U24ES026699 | Nucleic Acids Res (2022 Jul 05) |
35412637
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2022 |
Whole-genome profiling of DNA methylation and hydroxymethylation identifies distinct regulatory prog ... | Peng, Vincent; Xing, Xiaoyun; Bando, Jennifer K; Trsan, Tihana; Di Luccia, Blanda; Collins, Pa ... | U24ES026699 | Nat Immunol (2022 Apr) |
35332328
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2022 |
A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development. | Modzelewski, Andrew J; Shao, Wanqing; Chen, Jingqi; Lee, Angus; Qi, Xin; Noon, Mackenzie; Tjok ... | U24ES026699 | Cell (2021 10 28) |
34644528
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2021 |
AIAP: A Quality Control and Integrative Analysis Package to Improve ATAC-seq Data Analysis. | Liu, Shaopeng; Li, Daofeng; Lyu, Cheng; Gontarz, Paul M; Miao, Benpeng; Madden, Pamela A F; Wa ... | U24ES026699 | Genomics Proteomics Bioinformatics (2021 08) |
34273560
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2021 |
Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epi ... | Karlow, Jennifer A; Miao, Benpeng; Xing, Xiaoyun; Wang, Ting; Zhang, Bo | U24ES026699 | Commun Biol (2021 May 21) |
34021236
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2021 |
Epigenetic dynamics shaping melanophore and iridophore cell fate in zebrafish. | Jang, Hyo Sik; Chen, Yujie; Ge, Jiaxin; Wilkening, Alicia N; Hou, Yiran; Lee, Hyung Joo; Choi, ... | U24ES026699 | Genome Biol (2021 10 04) |
34607603
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2021 |
Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disea ... | Zhang, Bo; Kim, M Yvonne; Elliot, GiNell; Zhou, Yan; Zhao, Guangfeng; Li, Daofeng; Lowdon, Re ... | U24ES026699 | Dev Cell (2021 05 03) |
33891899
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2021 |
The Need for a Human Pangenome Reference Sequence. | Miga, Karen H; Wang, Ting | U24ES026699 | Annu Rev Genomics Hum Genet (2021 08 31) |
33929893
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2021 |
The qBED track: a novel genome browser visualization for point processes. | Moudgil, Arnav; Li, Daofeng; Hsu, Silas; Purushotham, Deepak; Wang, Ting; Mitra, Robi D | U24ES026699 | Bioinformatics (2021 May 23) |
32941613
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2021 |
Transcript assembly improves expression quantification of transposable elements in single-cell RNA-s ... | Shao, Wanqing; Wang, Ting | U24ES026699 | Genome Res (2021 01) |
33355230
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2021 |
A map of cis-regulatory elements and 3D genome structures in zebrafish. | Yang, Hongbo; Luan, Yu; Liu, Tingting; Lee, Hyung Joo; Fang, Li; Wang, Yanli; Wang, Xiaotao; ... | U24ES026699 | Nature (2020 12) |
33239788
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2020 |
An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infect ... | Kim, Arthur S; Zimmerman, Ofer; Fox, Julie M; Nelson, Christopher A; Basore, Katherine; Zhang, ... | U24ES026699 | Cell Host Microbe (2020 03 11) |
32075743
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2020 |
Cell-type-specific 3D epigenomes in the developing human cortex. | Song, Michael; Pebworth, Mark-Phillip; Yang, Xiaoyu; Abnousi, Armen; Fan, Changxu; Wen, Jia; R ... | U24ES026699 | Nature (2020 11) |
33057195
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2020 |
Cellular diversity of the regenerating caudal fin. | Hou, Yiran; Lee, Hyung Joo; Chen, Yujie; Ge, Jiaxin; Osman, Fujr Osman Ibrahim; McAdow, Anthon ... | U24ES026699 | Sci Adv (2020 08) |
32851162
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2020 |
Co-opted transposons help perpetuate conserved higher-order chromosomal structures. | Choudhary, Mayank Nk; Friedman, Ryan Z; Wang, Julia T; Jang, Hyo Sik; Zhuo, Xiaoyu; Wang, Ting | U24ES026699 | Genome Biol (2020 01 24) |
31973766
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2020 |
Comparison of differential accessibility analysis strategies for ATAC-seq data. | Gontarz, Paul; Fu, Shuhua; Xing, Xiaoyun; Liu, Shaopeng; Miao, Benpeng; Bazylianska, Viktoriia ... | U24ES026699 | Sci Rep (2020 06 23) |
32576878
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2020 |
DeepH&M: Estimating single-CpG hydroxymethylation and methylation levels from enrichment and restric ... | He, Yu; Jang, Hyo Sik; Xing, Xiaoyun; Li, Daofeng; Vasek, Michael J; Dougherty, Joseph D; Wang ... | U24ES026699 | Sci Adv (2020 07) |
32937429
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2020 |
Derivation of trophoblast stem cells from naïve human pluripotent stem cells. | Dong, Chen; Beltcheva, Mariana; Gontarz, Paul; Zhang, Bo; Popli, Pooja; Fischer, Laura A; Khan ... | U24ES026699 | Elife (2020 02 12) |
32048992
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2020 |
Epigenomic differences in the human and chimpanzee genomes are associated with structural variation. | Zhuo, Xiaoyu; Du, Alan Y; Pehrsson, Erica C; Li, Daofeng; Wang, Ting | U24ES026699 | Genome Res (2020 Dec 10) |
33303495
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2020 |
Epigenomics and genotype-phenotype association analyses reveal conserved genetic architecture of com ... | Liu, Shuli; Yu, Ying; Zhang, Shengli; Cole, John B; Tenesa, Albert; Wang, Ting; McDaneld, Tar ... | U24ES026699 | BMC Biol (2020 07 03) |
32620158
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2020 |
Exploring the coronavirus pandemic with the WashU Virus Genome Browser. | Flynn, Jennifer A; Purushotham, Deepak; Choudhary, Mayank N K; Zhuo, Xiaoyu; Fan, Changxu; Matt ... | U24ES026699 | Nat Genet (2020 Oct) |
32908257
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2020 |
Regenerating zebrafish fin epigenome is characterized by stable lineage-specific DNA methylation and ... | Lee, Hyung Joo; Hou, Yiran; Chen, Yujie; Dailey, Zea Z; Riddihough, Aiyana; Jang, Hyo Sik; Wan ... | U24ES026699 | Genome Biol (2020 02 27) |
32106888
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2020 |
Requisite Chromatin Remodeling for Myeloid and Erythroid Lineage Differentiation from Erythromyeloid ... | Wu, Jun; Krchma, Karen; Lee, Hyung Joo; Prabhakar, Sairam; Wang, Xiaoli; Zhao, Haiyong; Xing, ... | U24ES026699 | Cell Rep (2020 11 17) |
33207205
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2020 |
Robust principal component analysis for accurate outlier sample detection in RNA-Seq data. | Chen, Xiaoying; Zhang, Bo; Wang, Ting; Bonni, Azad; Zhao, Guoyan | U24ES026699 | BMC Bioinformatics (2020 Jun 29) |
32600248
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2020 |
Tissue-specific usage of transposable element-derived promoters in mouse development. | Miao, Benpeng; Fu, Shuhua; Lyu, Cheng; Gontarz, Paul; Wang, Ting; Zhang, Bo | U24ES026699 | Genome Biol (2020 09 28) |
32988383
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2020 |
A non-randomized procedure for large-scale heterogeneous multiple discrete testing based on randomiz ... | Dai, Xiaoyu; Lin, Nan; Li, Daofeng; Wang, Ting | U24ES026699 | Biometrics (2019 06) |
30387496
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2019 |
Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer's disease pathology an ... | Li, Peipei; Marshall, Lee; Oh, Gabriel; Jakubowski, Jennifer L; Groot, Daniel; He, Yu; Wang, ... | U24ES026699 | Nat Commun (2019 May 21) |
31113950
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2019 |
FeatSNP: An Interactive Database for Brain-Specific Epigenetic Annotation of Human SNPs. | Ma, Chun-Yu; Madden, Pamela; Gontarz, Paul; Wang, Ting; Zhang, Bo | U24ES026699 | Front Genet (2019) |
31001319
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2019 |
The epigenomic landscape of transposable elements across normal human development and anatomy. | Pehrsson, Erica C; Choudhary, Mayank N K; Sundaram, Vasavi; Wang, Ting | U24ES026699 | Nat Commun (2019 12 10) |
31822674
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2019 |
Transposable elements drive widespread expression of oncogenes in human cancers. | Jang, Hyo Sik; Shah, Nakul M; Du, Alan Y; Dailey, Zea Z; Pehrsson, Erica C; Godoy, Paula M; Zh ... | U24ES026699 | Nat Genet (2019 04) |
30926969
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2019 |
WashU Epigenome Browser update 2019. | Li, Daofeng; Hsu, Silas; Purushotham, Deepak; Sears, Renee L; Wang, Ting | U24ES026699 | Nucleic Acids Res (2019 07 02) |
31165883
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2019 |
A high-fat diet alters genome-wide DNA methylation and gene expression in SM/J mice. | Keleher, Madeline Rose; Zaidi, Rabab; Hicks, Lauren; Shah, Shyam; Xing, Xiaoyun; Li, Daofeng; ... | U24ES026699 | BMC Genomics (2018 Dec 07) |
30526554
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2018 |
Characterization of a Mouse Model of Börjeson-Forssman-Lehmann Syndrome. | Cheng, Cheng; Deng, Pan-Yue; Ikeuchi, Yoshiho; Yuede, Carla; Li, Daofeng; Rensing, Nicholas; H ... | U24ES026699 | Cell Rep (2018 11 06) |
30403997
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2018 |
Comprehensive Whole DNA Methylome Analysis by Integrating MeDIP-seq and MRE-seq. | Xing, Xiaoyun; Zhang, Bo; Li, Daofeng; Wang, Ting | U24ES026699 | Methods Mol Biol (2018) |
29224147
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2018 |
Genome-wide association study identifies a novel locus for cannabis dependence. | Agrawal, A; Chou, Y-L; Carey, C E; Baranger, D A A; Zhang, B; Sherva, R; Wetherill, L; Kapoor ... | U24ES026699 | Mol Psychiatry (2018 May) |
29112194
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2018 |
Genome-wide DNA methylation profiling of primary colorectal laterally spreading tumors identifies di ... | Zhu, Liangliang; Yan, Feihu; Wang, Zhen; Dong, Haiyan; Bian, Chengling; Wang, Ting; Yu, Enda; ... | U24ES026699 | Int J Cancer (2018 11 15) |
30183087
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2018 |
Long-Term In Vitro Expansion of Epithelial Stem Cells Enabled by Pharmacological Inhibition of PAK1- ... | Zhang, Chengkang; Lee, Hyung Joo; Shrivastava, Anura; Wang, Ruipeng; McQuiston, Travis J; Chall ... | U24ES026699 | Cell Rep (2018 10 16) |
30332641
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2018 |
Soluble inflammatory mediators induce transcriptional re-organization that is independent of dna met ... | Jiang, Kaiyu; Wong, Laiping; Chen, Yanmin; Xing, Xiaoyun; Li, Daofeng; Wang, Ting; Jarvis, Ja ... | U24ES026699 | J Reprod Immunol (2018 08) |
29800761
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2018 |
The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chr ... | Wang, Yanli; Song, Fan; Zhang, Bo; Zhang, Lijun; Xu, Jie; Kuang, Da; Li, Daofeng; Choudhary, ... | U24ES026699 | Genome Biol (2018 10 04) |
30286773
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2018 |
The NIEHS TaRGET II Consortium and environmental epigenomics. | Wang, Ting; Pehrsson, Erica C; Purushotham, Deepak; Li, Daofeng; Zhuo, Xiaoyu; Zhang, Bo; Laws ... | P30ES013508, P30ES017885, P30ES025128, R01ES028802, R01ES028802, U24ES026699 | Nat Biotechnol (2018 Mar 06) |
29509741
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2018 |
Transposable Element Mediated Innovation in Gene Regulatory Landscapes of Cells: Re-Visiting the "Ge ... | Sundaram, Vasavi; Wang, Ting | U24ES026699 | Bioessays (2018 Jan) |
29206283
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2018 |
DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism. | Shen, Jie; Wang, Cuicui; Li, Daofeng; Xu, Taotao; Myers, Jason; Ashton, John M; Wang, Ting; Z ... | U24ES026699 | JCI Insight (2017 Jun 15) |
28614801
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2017 |
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats. | Brocks, David; Schmidt, Christopher R; Daskalakis, Michael; Jang, Hyo Sik; Shah, Nakul M; Li, ... | U24ES026699 | Nat Genet (2017 Jul) |
28604729
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2017 |
EpiCompare: an online tool to define and explore genomic regions with tissue or cell type-specific e ... | He, Yu; Wang, Ting | U24ES026699 | Bioinformatics (2017 Oct 15) |
28605501
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2017 |
Epigenomic annotation of noncoding mutations identifies mutated pathways in primary liver cancer. | Lowdon, Rebecca F; Wang, Ting | U24ES026699 | PLoS One (2017) |
28333948
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2017 |
ETV2/ER71 regulates hematopoietic regeneration by promoting hematopoietic stem cell proliferation. | Xu, Can-Xin; Lee, Tae-Jin; Sakurai, Nagisa; Krchma, Karen; Liu, Fang; Li, Daofeng; Wang, Ting ... | U24ES026699 | J Exp Med (2017 Jun 05) |
28461595
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2017 |
Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus. | Sundaram, Vasavi; Choudhary, Mayank N K; Pehrsson, Erica; Xing, Xiaoyun; Fiore, Christopher; Pa ... | U24ES026699 | Nat Commun (2017 Mar 28) |
28348391
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2017 |
MicroRNAs Induce a Permissive Chromatin Environment that Enables Neuronal Subtype-Specific Reprogram ... | Abernathy, Daniel G; Kim, Woo Kyung; McCoy, Matthew J; Lake, Allison M; Ouwenga, Rebecca; Lee, ... | U24ES026699 | Cell Stem Cell (2017 09 07) |
28886366
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2017 |
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary seq ... | Zhou, Jia; Sears, Renee L; Xing, Xiaoyun; Zhang, Bo; Li, Daofeng; Rockweiler, Nicole B; Jang, ... | U24ES026699 | BMC Genomics (2017 Sep 12) |
28899353
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2017 |
Uncovering the transcriptomic and epigenomic landscape of nicotinic receptor genes in non-neuronal t ... | Zhang, Bo; Madden, Pamela; Gu, Junchen; Xing, Xiaoyun; Sankar, Savita; Flynn, Jennifer; Kroll, ... | U24ES026699 | BMC Genomics (2017 Jun 05) |
28583088
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2017 |
Whole-Genome DNA Methylation Profiling Identifies Epigenetic Signatures of Uterine Carcinosarcoma. | Li, Jing; Xing, Xiaoyun; Li, Daofeng; Zhang, Bo; Mutch, David G; Hagemann, Ian S; Wang, Ting | U24ES026699 | Neoplasia (2017 Feb) |
28088687
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2017 |
Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced Neurotoxicity. | Pan, Yanchun; Daito, Takuji; Sasaki, Yo; Chung, Yong Hee; Xing, Xiaoyun; Pondugula, Santhi; Sw ... | U24ES026699 | Sci Rep (2016 08 12) |
27516062
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2016 |