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Who We Fund: Publication Detail

Project Title: THE WASHU TARGET ENVIRONMENTAL EPIGENOMICS DATA COORDINATION CENTER
PI: Wang, Ting
Institution: Washington University
Grant Number: U24ES026699

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 60 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm?do=portfolio.grantpubdetail&&grant_number=U24ES026699&format=excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Capture Methylation-Sensitive Restriction Enzyme Sequencing (Capture MRE-Seq) for Methylation Analys ...   Xing, Xiaoyun; Karlow, Jennifer A; Li, Daofeng; Jang, Hyo Sik; Lee, Hyung Joo; Wang, Ting U24ES026699 Methods Mol Biol (2023) 37041441 Exiting the NIEHS site 2023 
Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements.   Shah, Nakul M; Jang, H Josh; Liang, Yonghao; Maeng, Ju Heon; Tzeng, Shin-Cheng; Wu, Angela; Ba ... U24ES026699 Nat Genet (2023 Apr) 36973455 Exiting the NIEHS site 2023 
Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes.   Choudhary, Mayank N K; Quaid, Kara; Xing, Xiaoyun; Schmidt, Heather; Wang, Ting U24ES026699 Nat Commun (2023 Feb 06) 36746940 Exiting the NIEHS site 2023 
Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis.   Karlow, Jennifer A; Devarakonda, Siddhartha; Xing, Xiaoyun; Jang, Hyo Sik; Govindan, Ramaswamy; ... U24ES026699 Cancer Res (2022 Aug 03) 35706127 Exiting the NIEHS site 2022 
Epigenomic analysis reveals prevalent contribution of transposable elements to cis-regulatory elemen ...   Lee, Hyung Joo; Hou, Yiran; Maeng, Ju Heon; Shah, Nakul M; Chen, Yujie; Lawson, Heather A; Yan ... U24ES026699 Genome Res (2022 Jul) 35649578 Exiting the NIEHS site 2022 
Exploring genomic data coupled with 3D chromatin structures using the WashU Epigenome Browser.   Li, Daofeng; Harrison, Jessica K; Purushotham, Deepak; Wang, Ting U24ES026699 Nat Methods (2022 Aug) 35864166 Exiting the NIEHS site 2022 
Genetic, epigenetic, and environmental mechanisms govern allele-specific gene expression.   St Pierre, Celine L; Macias-Velasco, Juan F; Wayhart, Jessica P; Yin, Li; Semenkovich, Clay F; ... U24ES026699 Genome Res (2022 Jun) 35501130 Exiting the NIEHS site 2022 
Mammalian genome innovation through transposon domestication.   Modzelewski, Andrew J; Gan Chong, Johnny; Wang, Ting; He, Lin U24ES026699 Nat Cell Biol (2022 Sep) 36008480 Exiting the NIEHS site 2022 
WashU Epigenome Browser update 2022.   Li, Daofeng; Purushotham, Deepak; Harrison, Jessica K; Hsu, Silas; Zhuo, Xiaoyu; Fan, Changxu; ... U24ES026699 Nucleic Acids Res (2022 Jul 05) 35412637 Exiting the NIEHS site 2022 
Whole-genome profiling of DNA methylation and hydroxymethylation identifies distinct regulatory prog ...   Peng, Vincent; Xing, Xiaoyun; Bando, Jennifer K; Trsan, Tihana; Di Luccia, Blanda; Collins, Pa ... U24ES026699 Nat Immunol (2022 Apr) 35332328 Exiting the NIEHS site 2022 
A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development.   Modzelewski, Andrew J; Shao, Wanqing; Chen, Jingqi; Lee, Angus; Qi, Xin; Noon, Mackenzie; Tjok ... U24ES026699 Cell (2021 10 28) 34644528 Exiting the NIEHS site 2021 
AIAP: A Quality Control and Integrative Analysis Package to Improve ATAC-seq Data Analysis.   Liu, Shaopeng; Li, Daofeng; Lyu, Cheng; Gontarz, Paul M; Miao, Benpeng; Madden, Pamela A F; Wa ... U24ES026699 Genomics Proteomics Bioinformatics (2021 08) 34273560 Exiting the NIEHS site 2021 
Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epi ...   Karlow, Jennifer A; Miao, Benpeng; Xing, Xiaoyun; Wang, Ting; Zhang, Bo U24ES026699 Commun Biol (2021 May 21) 34021236 Exiting the NIEHS site 2021 
Epigenetic dynamics shaping melanophore and iridophore cell fate in zebrafish.   Jang, Hyo Sik; Chen, Yujie; Ge, Jiaxin; Wilkening, Alicia N; Hou, Yiran; Lee, Hyung Joo; Choi, ... U24ES026699 Genome Biol (2021 10 04) 34607603 Exiting the NIEHS site 2021 
Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disea ...   Zhang, Bo; Kim, M Yvonne; Elliot, GiNell; Zhou, Yan; Zhao, Guangfeng; Li, Daofeng; Lowdon, Re ... U24ES026699 Dev Cell (2021 05 03) 33891899 Exiting the NIEHS site 2021 
The Need for a Human Pangenome Reference Sequence.   Miga, Karen H; Wang, Ting U24ES026699 Annu Rev Genomics Hum Genet (2021 08 31) 33929893 Exiting the NIEHS site 2021 
The qBED track: a novel genome browser visualization for point processes.   Moudgil, Arnav; Li, Daofeng; Hsu, Silas; Purushotham, Deepak; Wang, Ting; Mitra, Robi D U24ES026699 Bioinformatics (2021 May 23) 32941613 Exiting the NIEHS site 2021 
Transcript assembly improves expression quantification of transposable elements in single-cell RNA-s ...   Shao, Wanqing; Wang, Ting U24ES026699 Genome Res (2021 01) 33355230 Exiting the NIEHS site 2021 
A map of cis-regulatory elements and 3D genome structures in zebrafish.   Yang, Hongbo; Luan, Yu; Liu, Tingting; Lee, Hyung Joo; Fang, Li; Wang, Yanli; Wang, Xiaotao; ... U24ES026699 Nature (2020 12) 33239788 Exiting the NIEHS site 2020 
An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infect ...   Kim, Arthur S; Zimmerman, Ofer; Fox, Julie M; Nelson, Christopher A; Basore, Katherine; Zhang, ... U24ES026699 Cell Host Microbe (2020 03 11) 32075743 Exiting the NIEHS site 2020 
Cell-type-specific 3D epigenomes in the developing human cortex.   Song, Michael; Pebworth, Mark-Phillip; Yang, Xiaoyu; Abnousi, Armen; Fan, Changxu; Wen, Jia; R ... U24ES026699 Nature (2020 11) 33057195 Exiting the NIEHS site 2020 
Cellular diversity of the regenerating caudal fin.   Hou, Yiran; Lee, Hyung Joo; Chen, Yujie; Ge, Jiaxin; Osman, Fujr Osman Ibrahim; McAdow, Anthon ... U24ES026699 Sci Adv (2020 08) 32851162 Exiting the NIEHS site 2020 
Co-opted transposons help perpetuate conserved higher-order chromosomal structures.   Choudhary, Mayank Nk; Friedman, Ryan Z; Wang, Julia T; Jang, Hyo Sik; Zhuo, Xiaoyu; Wang, Ting U24ES026699 Genome Biol (2020 01 24) 31973766 Exiting the NIEHS site 2020 
Comparison of differential accessibility analysis strategies for ATAC-seq data.   Gontarz, Paul; Fu, Shuhua; Xing, Xiaoyun; Liu, Shaopeng; Miao, Benpeng; Bazylianska, Viktoriia ... U24ES026699 Sci Rep (2020 06 23) 32576878 Exiting the NIEHS site 2020 
DeepH&M: Estimating single-CpG hydroxymethylation and methylation levels from enrichment and restric ...   He, Yu; Jang, Hyo Sik; Xing, Xiaoyun; Li, Daofeng; Vasek, Michael J; Dougherty, Joseph D; Wang ... U24ES026699 Sci Adv (2020 07) 32937429 Exiting the NIEHS site 2020 
Derivation of trophoblast stem cells from naïve human pluripotent stem cells.   Dong, Chen; Beltcheva, Mariana; Gontarz, Paul; Zhang, Bo; Popli, Pooja; Fischer, Laura A; Khan ... U24ES026699 Elife (2020 02 12) 32048992 Exiting the NIEHS site 2020 
Epigenomic differences in the human and chimpanzee genomes are associated with structural variation.   Zhuo, Xiaoyu; Du, Alan Y; Pehrsson, Erica C; Li, Daofeng; Wang, Ting U24ES026699 Genome Res (2020 Dec 10) 33303495 Exiting the NIEHS site 2020 
Epigenomics and genotype-phenotype association analyses reveal conserved genetic architecture of com ...   Liu, Shuli; Yu, Ying; Zhang, Shengli; Cole, John B; Tenesa, Albert; Wang, Ting; McDaneld, Tar ... U24ES026699 BMC Biol (2020 07 03) 32620158 Exiting the NIEHS site 2020 
Exploring the coronavirus pandemic with the WashU Virus Genome Browser.   Flynn, Jennifer A; Purushotham, Deepak; Choudhary, Mayank N K; Zhuo, Xiaoyu; Fan, Changxu; Matt ... U24ES026699 Nat Genet (2020 Oct) 32908257 Exiting the NIEHS site 2020 
Regenerating zebrafish fin epigenome is characterized by stable lineage-specific DNA methylation and ...   Lee, Hyung Joo; Hou, Yiran; Chen, Yujie; Dailey, Zea Z; Riddihough, Aiyana; Jang, Hyo Sik; Wan ... U24ES026699 Genome Biol (2020 02 27) 32106888 Exiting the NIEHS site 2020 
Requisite Chromatin Remodeling for Myeloid and Erythroid Lineage Differentiation from Erythromyeloid ...   Wu, Jun; Krchma, Karen; Lee, Hyung Joo; Prabhakar, Sairam; Wang, Xiaoli; Zhao, Haiyong; Xing, ... U24ES026699 Cell Rep (2020 11 17) 33207205 Exiting the NIEHS site 2020 
Robust principal component analysis for accurate outlier sample detection in RNA-Seq data.   Chen, Xiaoying; Zhang, Bo; Wang, Ting; Bonni, Azad; Zhao, Guoyan U24ES026699 BMC Bioinformatics (2020 Jun 29) 32600248 Exiting the NIEHS site 2020 
Tissue-specific usage of transposable element-derived promoters in mouse development.   Miao, Benpeng; Fu, Shuhua; Lyu, Cheng; Gontarz, Paul; Wang, Ting; Zhang, Bo U24ES026699 Genome Biol (2020 09 28) 32988383 Exiting the NIEHS site 2020 
A non-randomized procedure for large-scale heterogeneous multiple discrete testing based on randomiz ...   Dai, Xiaoyu; Lin, Nan; Li, Daofeng; Wang, Ting U24ES026699 Biometrics (2019 06) 30387496 Exiting the NIEHS site 2019 
Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer's disease pathology an ...   Li, Peipei; Marshall, Lee; Oh, Gabriel; Jakubowski, Jennifer L; Groot, Daniel; He, Yu; Wang, ... U24ES026699 Nat Commun (2019 May 21) 31113950 Exiting the NIEHS site 2019 
FeatSNP: An Interactive Database for Brain-Specific Epigenetic Annotation of Human SNPs.   Ma, Chun-Yu; Madden, Pamela; Gontarz, Paul; Wang, Ting; Zhang, Bo U24ES026699 Front Genet (2019) 31001319 Exiting the NIEHS site 2019 
The epigenomic landscape of transposable elements across normal human development and anatomy.   Pehrsson, Erica C; Choudhary, Mayank N K; Sundaram, Vasavi; Wang, Ting U24ES026699 Nat Commun (2019 12 10) 31822674 Exiting the NIEHS site 2019 
Transposable elements drive widespread expression of oncogenes in human cancers.   Jang, Hyo Sik; Shah, Nakul M; Du, Alan Y; Dailey, Zea Z; Pehrsson, Erica C; Godoy, Paula M; Zh ... U24ES026699 Nat Genet (2019 04) 30926969 Exiting the NIEHS site 2019 
WashU Epigenome Browser update 2019.   Li, Daofeng; Hsu, Silas; Purushotham, Deepak; Sears, Renee L; Wang, Ting U24ES026699 Nucleic Acids Res (2019 07 02) 31165883 Exiting the NIEHS site 2019 
A high-fat diet alters genome-wide DNA methylation and gene expression in SM/J mice.   Keleher, Madeline Rose; Zaidi, Rabab; Hicks, Lauren; Shah, Shyam; Xing, Xiaoyun; Li, Daofeng; ... U24ES026699 BMC Genomics (2018 Dec 07) 30526554 Exiting the NIEHS site 2018 
Characterization of a Mouse Model of Börjeson-Forssman-Lehmann Syndrome.   Cheng, Cheng; Deng, Pan-Yue; Ikeuchi, Yoshiho; Yuede, Carla; Li, Daofeng; Rensing, Nicholas; H ... U24ES026699 Cell Rep (2018 11 06) 30403997 Exiting the NIEHS site 2018 
Comprehensive Whole DNA Methylome Analysis by Integrating MeDIP-seq and MRE-seq.   Xing, Xiaoyun; Zhang, Bo; Li, Daofeng; Wang, Ting U24ES026699 Methods Mol Biol (2018) 29224147 Exiting the NIEHS site 2018 
Genome-wide association study identifies a novel locus for cannabis dependence.   Agrawal, A; Chou, Y-L; Carey, C E; Baranger, D A A; Zhang, B; Sherva, R; Wetherill, L; Kapoor ... U24ES026699 Mol Psychiatry (2018 May) 29112194 Exiting the NIEHS site 2018 
Genome-wide DNA methylation profiling of primary colorectal laterally spreading tumors identifies di ...   Zhu, Liangliang; Yan, Feihu; Wang, Zhen; Dong, Haiyan; Bian, Chengling; Wang, Ting; Yu, Enda; ... U24ES026699 Int J Cancer (2018 11 15) 30183087 Exiting the NIEHS site 2018 
Long-Term In Vitro Expansion of Epithelial Stem Cells Enabled by Pharmacological Inhibition of PAK1- ...   Zhang, Chengkang; Lee, Hyung Joo; Shrivastava, Anura; Wang, Ruipeng; McQuiston, Travis J; Chall ... U24ES026699 Cell Rep (2018 10 16) 30332641 Exiting the NIEHS site 2018 
Soluble inflammatory mediators induce transcriptional re-organization that is independent of dna met ...   Jiang, Kaiyu; Wong, Laiping; Chen, Yanmin; Xing, Xiaoyun; Li, Daofeng; Wang, Ting; Jarvis, Ja ... U24ES026699 J Reprod Immunol (2018 08) 29800761 Exiting the NIEHS site 2018 
The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chr ...   Wang, Yanli; Song, Fan; Zhang, Bo; Zhang, Lijun; Xu, Jie; Kuang, Da; Li, Daofeng; Choudhary, ... U24ES026699 Genome Biol (2018 10 04) 30286773 Exiting the NIEHS site 2018 
The NIEHS TaRGET II Consortium and environmental epigenomics.   Wang, Ting; Pehrsson, Erica C; Purushotham, Deepak; Li, Daofeng; Zhuo, Xiaoyu; Zhang, Bo; Laws ... P30ES013508, P30ES017885, P30ES025128, R01ES028802, R01ES028802, U24ES026699 Nat Biotechnol (2018 Mar 06) 29509741 Exiting the NIEHS site 2018 
Transposable Element Mediated Innovation in Gene Regulatory Landscapes of Cells: Re-Visiting the "Ge ...   Sundaram, Vasavi; Wang, Ting U24ES026699 Bioessays (2018 Jan) 29206283 Exiting the NIEHS site 2018 
DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism.   Shen, Jie; Wang, Cuicui; Li, Daofeng; Xu, Taotao; Myers, Jason; Ashton, John M; Wang, Ting; Z ... U24ES026699 JCI Insight (2017 Jun 15) 28614801 Exiting the NIEHS site 2017 
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.   Brocks, David; Schmidt, Christopher R; Daskalakis, Michael; Jang, Hyo Sik; Shah, Nakul M; Li, ... U24ES026699 Nat Genet (2017 Jul) 28604729 Exiting the NIEHS site 2017 
EpiCompare: an online tool to define and explore genomic regions with tissue or cell type-specific e ...   He, Yu; Wang, Ting U24ES026699 Bioinformatics (2017 Oct 15) 28605501 Exiting the NIEHS site 2017 
Epigenomic annotation of noncoding mutations identifies mutated pathways in primary liver cancer.   Lowdon, Rebecca F; Wang, Ting U24ES026699 PLoS One (2017) 28333948 Exiting the NIEHS site 2017 
ETV2/ER71 regulates hematopoietic regeneration by promoting hematopoietic stem cell proliferation.   Xu, Can-Xin; Lee, Tae-Jin; Sakurai, Nagisa; Krchma, Karen; Liu, Fang; Li, Daofeng; Wang, Ting ... U24ES026699 J Exp Med (2017 Jun 05) 28461595 Exiting the NIEHS site 2017 
Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus.   Sundaram, Vasavi; Choudhary, Mayank N K; Pehrsson, Erica; Xing, Xiaoyun; Fiore, Christopher; Pa ... U24ES026699 Nat Commun (2017 Mar 28) 28348391 Exiting the NIEHS site 2017 
MicroRNAs Induce a Permissive Chromatin Environment that Enables Neuronal Subtype-Specific Reprogram ...   Abernathy, Daniel G; Kim, Woo Kyung; McCoy, Matthew J; Lake, Allison M; Ouwenga, Rebecca; Lee, ... U24ES026699 Cell Stem Cell (2017 09 07) 28886366 Exiting the NIEHS site 2017 
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary seq ...   Zhou, Jia; Sears, Renee L; Xing, Xiaoyun; Zhang, Bo; Li, Daofeng; Rockweiler, Nicole B; Jang, ... U24ES026699 BMC Genomics (2017 Sep 12) 28899353 Exiting the NIEHS site 2017 
Uncovering the transcriptomic and epigenomic landscape of nicotinic receptor genes in non-neuronal t ...   Zhang, Bo; Madden, Pamela; Gu, Junchen; Xing, Xiaoyun; Sankar, Savita; Flynn, Jennifer; Kroll, ... U24ES026699 BMC Genomics (2017 Jun 05) 28583088 Exiting the NIEHS site 2017 
Whole-Genome DNA Methylation Profiling Identifies Epigenetic Signatures of Uterine Carcinosarcoma.   Li, Jing; Xing, Xiaoyun; Li, Daofeng; Zhang, Bo; Mutch, David G; Hagemann, Ian S; Wang, Ting U24ES026699 Neoplasia (2017 Feb) 28088687 Exiting the NIEHS site 2017 
Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced Neurotoxicity.   Pan, Yanchun; Daito, Takuji; Sasaki, Yo; Chung, Yong Hee; Xing, Xiaoyun; Pondugula, Santhi; Sw ... U24ES026699 Sci Rep (2016 08 12) 27516062 Exiting the NIEHS site 2016 
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