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Publication Detail

Title: Cumene hydroperoxide-supported denitrification of 2-nitropropane in uninduced mouse liver microsomes.

Authors: Marker, E K; Kulkarni, A P

Published In Int J Biochem, (1986)

Abstract: Cumene hydroperoxide supported oxidative denitrification of 2-nitropropane was investigated in uninduced mouse liver microsomes. The cytochrome P-450 peroxygenase catalyzed reaction resulted in the production of nitrite and acetone. Several lines of evidence suggested the involvement of multiple forms of cytochrome P-450. Acetone production was at least two times greater than nitrite release possibly due to sequestration of nitrite in the reaction mixtures.

PubMed ID: 3743868 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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