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Publication Detail

Title: C-myc expression is reduced in antipain-treated proliferating C3H 10T1/2 cells.

Authors: Chang, J D; Billings, P C; Kennedy, A R

Published In Biochem Biophys Res Commun, (1985 Dec 17)

Abstract: In this report, we demonstrate that treatment of proliferating irradiated and nonirradiated C3H 10T1/2 cells with the protease inhibitor antipain is associated with a reduction in c-myc expression. Under conditions in which antipain treatment results in reduced c-myc transcripts, there is no effect on total RNA synthesis, growth rate, or saturation density. Antipain may be a useful inhibitor in which to further study the role of c-myc in cellular physiology.

PubMed ID: 2417599 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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