Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

National Institute of Environmental Health Sciences

Use this QR code to view the newest version of this document
Use this QR code to view the newest version of this document

Your Environment. Your Health.

Publication Detail

Title: "One-pot" syntheses of malondialdehyde adducts of nucleosides.

Authors: Szekely, Jozsef; Wang, Hao; Peplowski, Katherine M; Knutson, Charles G; Marnett, Lawrence J; Rizzo, Carmelo J

Published In Nucleosides Nucleotides Nucleic Acids, (2008 Feb)

Abstract: Short, "one-pot" syntheses of malondialdehyde adducts of deoxyguanosine, deoxyadenosine, and deoxycytidine are described. These syntheses proceed in improved yield and easier purification than previous syntheses and are well suited for the preparation of isotopically labeled nucleoside adducts for biomarker and metabolic studies.

PubMed ID: 18205065 Exiting the NIEHS site

MeSH Terms: DNA Adducts/chemical synthesis*; DNA Adducts/chemistry; Malondialdehyde/chemistry*; Nucleosides/chemical synthesis*; Nucleosides/chemistry

Back
to Top