Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

National Institute of Environmental Health Sciences

Use this QR code to view the newest version of this document

Your Environment. Your Health.

Publication Detail

Title: DNA polymerases at the eukaryotic fork-20 years later.

Authors: Pavlov, Youri I; Shcherbakova, Polina V

Published In Mutat Res, (2010 Mar 01)

Abstract: Function of the eukaryotic genome depends on efficient and accurate replication of anti-parallel DNA strands. Eukaryotic DNA polymerases have different properties adapted to perform a wide spectrum of DNA transactions. Here we focus on major players in the bulk replication, DNA polymerases of the B-family. We review the organization of the replication fork in eukaryotes in a historical perspective, analyze contemporary models and propose a new integrative model of the fork.

PubMed ID: 19682465 Exiting the NIEHS site

MeSH Terms: DNA Replication*; DNA-Directed DNA Polymerase/chemistry; DNA-Directed DNA Polymerase/metabolism*; Eukaryotic Cells; Models, Genetic*

Back
to Top
Last Reviewed: December 05, 2024