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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: Lung clearance of particles in two strains of rats.

Authors: Ferin, J; Morehouse, B

Published In Exp Lung Res, (1980 Aug)

Abstract: Two strains of commonly used experimental rats were compared with regard to lung clearance of TiO2 particles. The Fisher 344 inbred rats retained predictably fewer particles after a 7-hr exposure than the larger outbred Long-Evans rats. This fact can be expected in view of the different lung size of the two strains. In addition, clearance of the retained particles was significantly slower in Fisher 344 rats. Differences in lung clearance capacity of different animal strains should be considered when experiments in inhalation toxicology are performed.

PubMed ID: 7250091 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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