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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: Acute changes in heart rate variability in subjects with diabetes following a highway traffic exposure.

Authors: Laumbach, Robert J; Rich, David Q; Gandhi, Sampada; Amorosa, Louis; Schneider, Stephen; Zhang, Junfeng; Ohman-Strickland, Pamela; Gong, Jicheng; Lelyanov, Oleksiy; Kipen, Howard M

Published In J Occup Environ Med, (2010 Mar)

Abstract: To pilot a protocol to evaluate acute cardiovascular effects in in-vehicle exposure to traffic air pollutants in people with diabetes.Twenty-one volunteers with type 2 diabetes were passengers on 90- to 110-minute car rides on a busy highway. We measured in-vehicle particle number and mass (PM2.5) nitrogen dioxide, and carbon monoxide and heart rate, heart rate variability (HRV), and blood pressure.Compared with pre-ride measurements, we found a decrease in high frequency (HF) HRV from pre-ride to next day (ratio 0.66, 95% CI = 0.47 to 0.93) and an increase in low frequency to HF ratio at post-ride (ratio 1.92, 95% CI = 1.21 to 3.05) at post-ride. Interquartile range increases in measured pollutants were associated with next-day decreases in HR HRV.This protocol appears useful for assessing acute adverse cardiovascular effects of in-vehicle exposures among people who have diabetes.

PubMed ID: 20190650 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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