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Title: Illustrating bias due to conditioning on a collider.

Authors: Cole, Stephen R; Platt, Robert W; Schisterman, Enrique F; Chu, Haitao; Westreich, Daniel; Richardson, David; Poole, Charles

Published In Int J Epidemiol, (2010 Apr)

Abstract: That conditioning on a common effect of exposure and outcome may cause selection, or collider-stratification, bias is not intuitive. We provide two hypothetical examples to convey concepts underlying bias due to conditioning on a collider. In the first example, fever is a common effect of influenza and consumption of a tainted egg-salad sandwich. In the second example, case-status is a common effect of a genotype and an environmental factor. In both examples, conditioning on the common effect imparts an association between two otherwise independent variables; we call this selection bias.

PubMed ID: 19926667 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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