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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: Iron metabolism and the innate immune response to infection.

Authors: Johnson, Erin E; Wessling-Resnick, Marianne

Published In Microbes Infect, (2012 Mar)

Abstract: Host antimicrobial mechanisms reduce iron availability to pathogens. Iron proteins influencing the innate immune response include hepcidin, lactoferrin, siderocalin, haptoglobin, hemopexin, Nramp1, ferroportin and the transferrin receptor. Numerous global health threats are influenced by iron status and provide examples of our growing understanding of the connections between infection and iron metabolism.

PubMed ID: 22033148 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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