Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

National Institute of Environmental Health Sciences

Use this QR code to view the newest version of this document
Use this QR code to view the newest version of this document

Your Environment. Your Health.

Publication Detail

Title: Targeting airway smooth muscle in airways diseases: an old concept with new twists.

Authors: Koziol-White, Cynthia J; Damera, Gautam; Panettieri Jr, Reynold A

Published In Expert Rev Respir Med, (2011 Dec)

Abstract: Airway smooth muscle (ASM) manifests a hyper-responsive phenotype in airway disorders such as asthma. ASM also modulates immune responses by secreting mediators and expressing cell-surface molecules that promote recruitment of inflammatory cells to the lungs. The aim of the current article is to highlight therapeutics that may modulate ASM responses in airway disorders and exacerbations.

PubMed ID: 22082163 Exiting the NIEHS site

MeSH Terms: Ablation Techniques*; Animals; Anti-Inflammatory Agents/therapeutic use; Asthma/immunology; Asthma/physiopathology; Asthma/therapy*; Bronchial Hyperreactivity/immunology; Bronchial Hyperreactivity/physiopathology; Bronchial Hyperreactivity/therapy*; Bronchoconstriction/drug effects; Bronchodilator Agents/therapeutic use; Humans; Immunotherapy*/methods; Lung*/drug effects; Lung*/immunology; Lung*/physiopathology; Lung*/surgery; Muscle, Smooth*/drug effects; Muscle, Smooth*/immunology; Muscle, Smooth*/physiopathology; Muscle, Smooth*/surgery; Respiratory System Agents/therapeutic use*; Treatment Outcome

Back
to Top