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Publication Detail

Title: Biochemical premotor biomarkers for Parkinson's disease.

Authors: Mollenhauer, Brit; Zhang, Jing

Published In Mov Disord, (2012 Apr 15)

Abstract: A biomarker is a biological characteristic that is objectively measured and evaluated as an indicator of normal biological or pathologic processes or of pharmacologic responses to a therapeutic intervention. We reviewed the current status of target protein biomarkers (eg, total/oligomeric ýý-synuclein and DJ-1) in cerebrospinal fluid, as well as on unbiased processes that can be used to discover novel biomarkers. We have also provide details about strategies toward potential populations/models and technologies, including the need for standardized sampling techniques, to pursue the identification of new biochemical markers in the premotor stage of Parkinson's disease in the future.

PubMed ID: 22508282 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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