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National Institute of Environmental Health Sciences

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Publication Detail

Title: Platelet storage and transfusions: new concerns associated with an old therapy.

Authors: Sahler, Julie; Grimshaw, Katie; Spinelli, Sherry L; Refaai, Majed A; Phipps, Richard P; Blumberg, Neil

Published In Drug Discov Today Dis Mech, (2011)

Abstract: Platelet transfusion has long been practiced with rudimentary knowledge about optimal storage conditions and their implications for efficacy and, particularly, safety. Recent concerns about complications such as inflammation, thrombosis and altered recipient immunity have been raised about platelet transfusion. This review will discuss recent important findings that have raised these issues about platelet transfusion associated morbidity, mortality and the possible role of platelet storage in these associations.

PubMed ID: 22662018 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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