Title: Epigenetic abnormalities in cancer find a "home on the range".
Authors: Easwaran, Hariharan; Baylin, Stephen B
Published In Cancer Cell, (2013 Jan 14)
Abstract: Recent studies have highlighted large genomic regions prone to undergo epigenetic changes in cancers. In this issue of Cancer Cell, Bert and colleagues describe novel genomic domains with aberrant epigenetic changes involving concordant activation of neighboring genes. These domains involve aberrant CpG-island hypermethylation similar to that observed in gene silencing.
PubMed ID: 23328477
MeSH Terms: No MeSH terms associated with this publication