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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: Petrochemical exposure and menstrual disturbances.

Authors: Thurston, S W; Ryan, L; Christiani, D C; Snow, R; Carlson, J; You, L; Cui, S; Ma, G; Wang, L; Huang, Y; Xu, X

Published In Am J Ind Med, (2000 Nov)

Abstract: An exploratory, cross-sectional retrospective study was conducted to examine the effects of benzene exposure on menstrual problems.The study was based on a survey administered to over 3,000 women who worked in a large petrochemical company in Beijing, China. An abnormal menstrual cycle length (AMCL), defined as an average menstrual cycle length of greater than 35 days or less than 21 days, is the major outcome of interest.After 7 years of benzene exposure, the adjusted odds ratio of having AMCL for each additional 5 years of exposure was 1.71 (95% CI 1.27-2.31). Feeling stressed at work was also an important predictor.This study suggests a significant association of benzene exposure and perceived stress with menstrual disturbance. A prospective study is needed to confirm this finding.

PubMed ID: 11025497 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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