Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Your Environment. Your Health.

Publication Detail

Title: Transgenerational effects of obesogens and the obesity epidemic.

Authors: Chamorro-García, Raquel; Blumberg, Bruce

Published In Curr Opin Pharmacol, (2014 Dec)

Abstract: In the last three decades there has been a dramatic, worldwide increase in the incidence of obesity, particularly in Western societies. This trend has required a significant economic investment to treat obesity-related disorders such as type 2 diabetes, cardiovascular disease, and non-alcoholic fatty liver disease. There is an urgent need to understand the factors that contribute to this increase in obesity in order to find new tools that will improve quality of life in affected individuals and to avoid the propagation of obesity to future generations. Endocrine disrupting chemicals have become an important piece of the obesity epidemic puzzle but little is known about the mechanism underlying their effects. In this commentary, we highlight recent work showing that the consequences of ancestral exposure to obesogenic chemicals results in the transmission of obesity-related phenotypes through at least three generations.

PubMed ID: 25460228 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

to Top