Title: A preliminary method development study to identify potential stroke biomarkers in plasma using multiple chromatographies with nanoLC-ESIMS detection.
Authors: Kodali, Phanichand; Landero-Figueroa, Julio A; Caruso, Joseph; Adeoye, Opeolu
Published In J Neural Transm (Vienna), (2013 Oct)
Abstract: Stroke is the leading cause of disability in the USA. Rapid, reliable diagnosis via a point-of-care blood test may facilitate earlier treatment to reduce disability. We have recently reported detailed methods of chromatographic separations of plasma samples coupled with nanoESI-ion trap a list of proteins which are viable candidates for further investigation as stroke biomarkers.
PubMed ID: 23580158
MeSH Terms: Biomarkers/blood*; Chromatography, High Pressure Liquid/methods*; Humans; Spectrometry, Mass, Electrospray Ionization/methods*; Stroke/blood*