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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: Prenatal Exposure to Cadmium and Cotinine and CpG island DNA methylation in Mother-Infant Pairs.

Authors: Gona, Saideep; Sanders, Alison P; Miranda, Marie Lynn; Fry, Rebecca C

Published In Genom Data, (2015 Sep 01)

Abstract: A precise biological mechanism by which cadmium acts as a developmental toxicant is unknown but is suggested to include an epigenetic basis. In prior work, we analyzed CpG island methylation levels within gene promoters (n=16,421) in leukocytes collected from mothers and their infants from a pregnancy cohort in Durham County, North Carolina. The CpG methylation levels were examined in relationship to prenatal exposure to cadmium and/or cotinine to identify genes and pathways influenced by in utero exposure. In the present article, we provide an enhanced description of the data collection and processing to facilitate cross-study comparisons. Data are available within the Gene Expression Omnibus database (GSE67976).

PubMed ID: 26295018 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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