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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: Nano-enabled delivery of diverse payloads across complex biological barriers.

Authors: Ross, Kathleen A; Brenza, Timothy M; Binnebose, Andrea M; Phanse, Yashdeep; Kanthasamy, Anumantha G; Gendelman, Howard E; Salem, Aliasger K; Bartholomay, Lyric C; Bellaire, Bryan H; Narasimhan, Balaji

Published In J Control Release, (2015 Dec 10)

Abstract: Complex biological barriers are major obstacles for preventing and treating disease. Nanocarriers are designed to overcome such obstacles by enhancing drug delivery through physiochemical barriers and improving therapeutic indices. This review critically examines both biological barriers and nanocarrier payloads for a variety of drug delivery applications. A spectrum of nanocarriers is discussed that have been successfully developed for improving tissue penetration for preventing or treating a range of infectious, inflammatory, and degenerative diseases.

PubMed ID: 26315817 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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