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Publication Detail

Title: Molecular mechanisms and genomic maps of DNA excision repair in Escherichia coli and humans.

Authors: Hu, Jinchuan; Selby, Christopher P; Adar, Sheera; Adebali, Ogun; Sancar, Aziz

Published In J Biol Chem, (2017 09 22)

Abstract: Nucleotide excision repair is a major DNA repair mechanism in all cellular organisms. In this repair system, the DNA damage is removed by concerted dual incisions bracketing the damage and at a precise distance from the damage. Here, we review the basic mechanisms of excision repair in Escherichia coli and humans and the recent genome-wide mapping of DNA damage and repair in these organisms at single-nucleotide resolution.

PubMed ID: 28798238 Exiting the NIEHS site

MeSH Terms: Chromosome Mapping/methods*; DNA Damage; DNA Repair/genetics*; Escherichia coli/genetics*; Humans

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