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Title: Upregulated P-Rex1 exacerbates human airway smooth muscle hyperplasia in asthma.

Authors: Huang, Yapei; Xie, Yan; Jiang, Haihong; Abel, Peter W; Panettieri Jr, Reynold A; Casale, Thomas B; Tu, Yaping

Published In J Allergy Clin Immunol, (2019 02)

Abstract: Abstract not available from PubMed.

PubMed ID: 30312708 Exiting the NIEHS site

MeSH Terms: Airway Obstruction/genetics; Airway Obstruction/metabolism*; Airway Remodeling/genetics; Asthma/genetics; Asthma/metabolism*; Cells, Cultured; Guanine Nucleotide Exchange Factors/genetics; Guanine Nucleotide Exchange Factors/metabolism*; Humans; Hyperplasia; Myocytes, Smooth Muscle/metabolism*; Myocytes, Smooth Muscle/pathology; Neoplasm Metastasis/genetics; Receptor, Platelet-Derived Growth Factor beta/metabolism; Respiratory System/pathology*; Up-Regulation; rac1 GTP-Binding Protein/genetics; rac1 GTP-Binding Protein/metabolism*

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