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Publication Detail

Title: Pach-ing It in: The Peculiar Organization of Mammalian Pachytene Chromosomes.

Authors: Jung, Yoon Hee; Corces, Victor G

Published In Mol Cell, (2019 02 07)

Abstract: In this issue of Molecular Cell, Wang et al. (2019) use Hi-C to visualize at high resolution the complex reprogramming of chromatin architecture during spermatogenesis in rhesus monkeys and mice. They find that pachytene spermatocytes have a unique chromosome organization that may result from the presence of the synaptonemal complex and transcription-associated proteins.

PubMed ID: 30735652 Exiting the NIEHS site

MeSH Terms: Animals; Chromatin*; Chromosomes, Mammalian; Male; Mice; Spermatocytes; Spermatogenesis*; Synaptonemal Complex

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