Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

National Institute of Environmental Health Sciences

Use this QR code to view the newest version of this document
Use this QR code to view the newest version of this document

Your Environment. Your Health.

Publication Detail

Title: Opportunities for evaluating chemical exposures and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) Program.

Authors: Buckley, Jessie P; Barrett, Emily S; Beamer, Paloma I; Bennett, Deborah H; Bloom, Michael S; Fennell, Timothy R; Fry, Rebecca C; Funk, William E; Hamra, Ghassan B; Hecht, Stephen S; Kannan, Kurunthachalam; Iyer, Ramsunder; Karagas, Margaret R; Lyall, Kristen; Parsons, Patrick J; Pellizzari, Edo D; Signes-Pastor, Antonio J; Starling, Anne P; Wang, Aolin; Watkins, Deborah J; Zhang, Mingyu; Woodruff, Tracey J; program collaborators for ECHO

Published In J Expo Sci Environ Epidemiol, (2020 May)

Abstract: The Environmental Influences on Child Health Outcomes (ECHO) Program will evaluate environmental factors affecting children's health (perinatal, neurodevelopmental, obesity, respiratory, and positive health outcomes) by pooling cohorts composed of >50,000 children in the largest US study of its kind. Our objective was to identify opportunities for studying chemicals and child health using existing or future ECHO chemical exposure data. We described chemical-related information collected by ECHO cohorts and reviewed ECHO-relevant literature on exposure routes, sources, and environmental and human monitoring. Fifty-six ECHO cohorts have existing or planned chemical biomonitoring data for mothers or children. Environmental phenols/parabens, phthalates, metals/metalloids, and tobacco biomarkers are each being measured by ≥15 cohorts, predominantly during pregnancy and childhood, indicating ample opportunities to study child health outcomes. Cohorts are collecting questionnaire data on multiple exposure sources and conducting environmental monitoring including air, dust, and water sample collection that could be used for exposure assessment studies. To supplement existing chemical data, we recommend biomonitoring of emerging chemicals, nontargeted analysis to identify novel chemicals, and expanded measurement of chemicals in alternative biological matrices and dust samples. ECHO's rich data and samples represent an unprecedented opportunity to accelerate environmental chemical research to improve the health of US children.

PubMed ID: 32066883 Exiting the NIEHS site

MeSH Terms: Adult; Biomarkers; Child; Child Health*; Child, Preschool; Dust/analysis; Environmental Exposure/analysis; Environmental Exposure/statistics & numerical data*; Environmental Health; Environmental Monitoring/statistics & numerical data; Environmental Pollutants/analysis; Female; Humans; Outcome Assessment, Health Care; Phenols/analysis; Pregnancy; United States

Back
to Top