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Your Environment. Your Health.

Publication Detail

Title: WellExplorer: an integrative resource linking hydraulic fracturing chemicals with hormonal pathways and geographic location.

Authors: Wetherbee, Owen; Meeker, Jessica R; DeVoto, Caroline; Penning, Trevor M; Moore, Jason H; Boland, Mary Regina

Published In Database (Oxford), (2020 01 01)

Abstract: Exposure to hydraulic fracturing fluid in drinking water increases the risk of many adverse health outcomes. Unfortunately, most individuals and researchers are unaware of the health risks posed by a particular well due to the diversity of chemical ingredients used across sites. We constructed WellExplorer (, an interactive tool for researchers and community members to use for retrieving information regarding the hormonal, testosterone and estrogen modulators located at each well. We found that wells in Alabama use a disproportionately high number of ingredients targeting estrogen pathways, while Illinois, Ohio and Pennsylvania use a disproportionately high number of ingredients targeting testosterone pathways. Researchers can utilize WellExplorer to study health outcomes related to exposure to fracturing chemicals in their population-based cohorts. Community members can use this resource to search their home or work locations (e.g. town or zip code) to determine proximity between where they live or work and specific hormonal exposures.

PubMed ID: 32701164 Exiting the NIEHS site

MeSH Terms: Databases, Factual*; Environmental Exposure*; Geography, Medical; Hormones/metabolism*; Humans; Hydraulic Fracking*; United States; Water Pollutants, Chemical*

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