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National Institute of Environmental Health Sciences

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Publication Detail

Title: Antenatal and neonatal factors contributing to extra uterine growth failure (EUGR) among preterm infants in Boston Birth Cohort (BBC).

Authors: Makker, Kartikeya; Ji, Yuelong; Hong, Xiumei; Wang, Xiaobin

Published In J Perinatol, (2021 05)

Abstract: OBJECTIVE: Identify antenatal and neonatal factors associated with primary outcome of EUGR. METHODS: 1063 preterm infants from a subset of the BBC were included in this prospective cohort study. Regression analysis was carried out to evaluate associations of EUGR with antenatal factors and neonatal factors. RESULTS: 6.1% of the infants had in-utero growth restriction (IUGR) at birth and 21.7% of infants had EUGR. The adjusted odds ratio for EUGR status were significant for birth weight (OR 0.99, p = 0.00, CI 0.99-0.99), for GA at birth (OR 4.58, p = 0.00, CI 3.25-6.44), for PDA (OR 2.9, p = 0.02, CI 1.17-7.1), for NEC (OR 5.14, p = 0.012, CI 1.44-18.3) and for day of life of reaching full feeds (OR 1.04, p = 0.001, CI 1.01-1.06). CONCLUSION: This study highlights important factors associated with EUGR. Additional studies are needed to gain further insight.

PubMed ID: 33589730 Exiting the NIEHS site

MeSH Terms: Birth Weight; Boston/epidemiology; Female; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature*; Pregnancy; Prospective Studies

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